Processing

Please wait...

Settings

Settings

Goto Application

1. WO2011011099 - MULTI-LAYERED GRADIENT VAGINAL RING

Publication Number WO/2011/011099
Publication Date 27.01.2011
International Application No. PCT/US2010/030183
International Filing Date 07.04.2010
Chapter 2 Demand Filed 17.12.2010
IPC
A61K 9/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
A61K 31/565 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
56Compounds containing cyclopentahydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
565not substituted in position 17 beta by a carbon atom, e.g. oestrane, oestradiol
CPC
A61K 31/565
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives, e.g. steroids
565not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
A61K 9/0036
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
0012Galenical forms characterised by the site of application
0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
0036Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
A61P 15/18
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
15Drugs for genital or sexual disorders
18Feminine contraceptives
A61P 31/18
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
14for RNA viruses
18for HIV
Applicants
  • THE POPULATION COUNCIL, INC. [US]/[US] (AllExceptUS)
  • VARIANO, Bruce [US]/[US] (UsOnly)
  • SPECK, Jeffrey [US]/[US] (UsOnly)
  • SALLENT, Maria, Teresa [US]/[US] (UsOnly)
  • EVANS, Simone [US]/[US] (UsOnly)
Inventors
  • VARIANO, Bruce
  • SPECK, Jeffrey
  • SALLENT, Maria, Teresa
  • EVANS, Simone
Agents
  • KRUMHOLZ, Arnold, H.
Priority Data
61/271,39121.07.2009US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) MULTI-LAYERED GRADIENT VAGINAL RING
(FR) ANNEAU VAGINAL À GRADIENT MULTICOUCHE
Abstract
(EN)
Multi-layered vaginal rings 2 comprising silicone elastomers and pharmaceutically active ingredients are disclosed. The rings comprise a number of layers, at least one of which contains a pharmaceutically active ingredient, and each of which is a silicone elastomer. The multiple layers preferably are produced from these layers of different compositions, including an inner layer 4, a middle layer 5, and an outer layer 6. After extrusion and simultaneous curing, however, the ring 2 includes a contiguous body which comprises a continuous silicone body providing unimpeded diffusion of the pharmaceutically active ingredient from the inner layer (s) 4 to the outer layer (s) 6. Methods of producing these vaginal rings and of using them are also disclosed.
(FR)
L'invention concerne des anneaux vaginaux multicouches (2) comprenant des élastomères de silicone et des principes pharmaceutiquement actifs. Les anneaux comprennent un certain nombre de couches, dont au moins une contient un principe pharmaceutiquement actif, et toutes sont en élastomère de silicone. Les multiples couches sont, de préférence, produites à partir de ces couches de compositions différentes, y compris une couche intérieure (4), une couche intermédiaire (5) et une couche extérieure (6). Cependant, après extrusion et durcissement simultané, l'anneau 2 comprend un corps contigu qui comprend un corps en silicone continu offrant une diffusion libre du principe pharmaceutiquement actif, de la ou des couches intérieures 4 à la ou aux couches extérieures (6). L'invention porte également sur des procédés de production de ces anneaux vaginaux et d'utilisation de ceux-ci.
Latest bibliographic data on file with the International Bureau