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1. WO2011010015 - PIPERIDINE COMPOUNDS, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME

Publication Number WO/2011/010015
Publication Date 27.01.2011
International Application No. PCT/FR2010/000520
International Filing Date 20.07.2010
IPC
C07D 211/42 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
211Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
04with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
06having no double bonds between ring members or between ring members and non-ring members
36with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
40Oxygen atoms
42attached in position 3 or 5
A61K 31/445 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
44Non-condensed pyridines; Hydrogenated derivatives thereof
445Non-condensed piperidines, e.g. piperocaine
A61K 31/4462 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
44Non-condensed pyridines; Hydrogenated derivatives thereof
445Non-condensed piperidines, e.g. piperocaine
4462only substituted in position 3
A61P 25/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
CPC
C07D 211/42
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
211Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
04with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
06having no double bonds between ring members or between ring members and non-ring members
36with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
40Oxygen atoms
42attached in position 3 or 5
Y02P 20/55
YSECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
20Technologies relating to chemical industry
50Improvements relating to the production of bulk chemicals
55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Applicants
  • LES LABORATOIRES SERVIER [FR]/[FR] (AllExceptUS)
  • UNIVERSITE DE NANTES [FR]/[FR] (AllExceptUS)
  • BOTEZ, Luliana [FR]/[FR] (UsOnly)
  • LEBRETON, Jacques [FR]/[FR] (UsOnly)
  • LESTAGE, Pierre [FR]/[FR] (UsOnly)
  • LOUIS, Caroline [FR]/[FR] (UsOnly)
  • MATHE, Monique [FR]/[FR] (UsOnly)
  • GAIGNARD, Daniel-Henri [FR]/[FR] (UsOnly)
Inventors
  • BOTEZ, Luliana
  • LEBRETON, Jacques
  • LESTAGE, Pierre
  • LOUIS, Caroline
  • MATHE, Monique
  • GAIGNARD, Daniel-Henri
Priority Data
09/0357321.07.2009FR
Publication Language French (FR)
Filing Language French (FR)
Designated States
Title
(EN) PIPERIDINE COMPOUNDS, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME
(FR) COMPOSES PIPERIDINIQUES, LEUR PROCEDE DE PREPARATION ET LES COMPOSITIONS PHARMACEUTIQUES QUI LES CONTIENNENT
Abstract
(EN)
The invention relates to the compounds of formula (I), where: R1 is a hydrogen atom or a methyl grouping; and R2 is a bromine atom, a fluorine atom or a trifluoromethyl grouping. The invention can be used for drugs.
(FR)
Composés de formule (I) : dans laquelle : > R1 représente un atome d'hydrogène ou un groupement méthyle, > R2 représente un atome de brome, un. atome de fluor ou un groupement trifluorométhyle, Médicaments.
Latest bibliographic data on file with the International Bureau