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1. WO2011009883 - SELECTIVE CB2 RECEPTOR AGONISTS FOR USE IN THE PREVENTION OR TREATMENT OF ALCOHOLIC LIVER DISEASE

Publication Number WO/2011/009883
Publication Date 27.01.2011
International Application No. PCT/EP2010/060556
International Filing Date 21.07.2010
IPC
A61K 31/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
A61K 31/352 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
35having six-membered rings with one oxygen as the only ring hetero atom
352condensed with carbocyclic rings, e.g. cannabinols, methantheline
A61P 1/16 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
16for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
CPC
A61K 31/352
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
35having six-membered rings with one oxygen as the only ring hetero atom
352condensed with carbocyclic rings, e.g. cannabinols, methantheline
A61P 1/16
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
16for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
Applicants
  • INSERM (Institut National de la Santé et de la Recherche Médicale) [FR]/[FR] (AllExceptUS)
  • LOTERSZTAJN, Sophie [FR]/[FR] (UsOnly)
  • TEIXEIRA-CLERC, Fatima [FR]/[FR] (UsOnly)
  • MALLAT, Ariane [FR]/[FR] (UsOnly)
  • LOUVET, Alexandre [FR]/[FR] (UsOnly)
Inventors
  • LOTERSZTAJN, Sophie
  • TEIXEIRA-CLERC, Fatima
  • MALLAT, Ariane
  • LOUVET, Alexandre
Agents
  • HIRSCH, Denise
Priority Data
09305700.823.07.2009EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) SELECTIVE CB2 RECEPTOR AGONISTS FOR USE IN THE PREVENTION OR TREATMENT OF ALCOHOLIC LIVER DISEASE
(FR) AGONISTES SÉLECTIFS DU RÉCEPTEUR CB2 DESTINÉS À ÊTRE UTILISÉS DANS LA PRÉVENTION OU LE TRAITEMENT D'UNE MALADIE HÉPATIQUE ALCOOLIQUE
Abstract
(EN)
The present invention relates to selective CB2 agonists for use in the prevention or treatment of alcoholic liver disease and particularly alcoholic hepatic steatosis and liver inflammation, and pharmaceutical composition thereof.
(FR)
La présente invention concerne des agonistes sélectifs du CB2 destinés à être utilisés dans la prévention ou le traitement d'une maladie hépatique alcoolique et en particulier une stéatose hépatique alcoolique et une inflammation hépatique, et une composition pharmaceutique de ceux-ci.
Also published as
Latest bibliographic data on file with the International Bureau