Processing

Please wait...

Settings

Settings

Goto Application

1. WO2011009089 - SMALL NON-CODING REGULATORY RNAs AND METHODS FOR THEIR USE

Publication Number WO/2011/009089
Publication Date 20.01.2011
International Application No. PCT/US2010/042346
International Filing Date 16.07.2010
IPC
C07H 21/02 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
21Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
02with ribosyl as saccharide radical
G01N 33/48 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
CPC
C12N 15/113
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
11DNA or RNA fragments; Modified forms thereof
113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
C12N 2310/111
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2310Structure or type of the nucleic acid
10Type of nucleic acid
11Antisense
111spanning the whole gene, or a large part of it
C12Q 1/6883
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms
68involving nucleic acids
6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
6883for diseases caused by alterations of genetic material
C12Q 1/6886
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms
68involving nucleic acids
6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
6883for diseases caused by alterations of genetic material
6886for cancer
C12Q 2600/156
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
2600Oligonucleotides characterized by their use
156Polymorphic or mutational markers
C12Q 2600/178
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
2600Oligonucleotides characterized by their use
178miRNA, siRNA or ncRNA
Applicants
  • ORDWAY RESEARCH INSTITUTE, INC. [US]/[US] (AllExceptUS)
  • GLINSKY, Gennadi, V. [US]/[US] (UsOnly)
Inventors
  • GLINSKY, Gennadi, V.
Agents
  • ELRIFI, Ivor, R.
Priority Data
61/226,44817.07.2009US
61/263,55623.11.2009US
61/264,05724.11.2009US
61/307,66624.02.2010US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) SMALL NON-CODING REGULATORY RNAs AND METHODS FOR THEIR USE
(FR) PETITS ARN RÉGULATEURS NON CODANTS ET LEURS PROCÉDÉS D'UTILISATION
Abstract
(EN)
Disclosed are methods and compositions related to small, non-coding RNA molecules having gene regulatory activity, compositions comprising same, and methods for their use. Provided are isolated small non-coding RNA molecules transcribed from an intergenic region of the human genome, wherein the intergenic region contains at least one small nucleotide polymorphism (SNP) associated with one or more human diseases or disorders. Also disclosed are methods for the detection of these small non-coding RNA molecules in a biological sample and related therapeutic, diagnostic, and prognostic methods.
(FR)
L'invention concerne des procédés et des compositions associées à de petites molécules d'ARN non codantes ayant une activité régulatrice d'un gène, des compositions comprenant celles-ci et leurs procédés d'utilisation. L'invention concerne de petites molécules d'ARN non codantes isolées transcrites à partir d'une région intergénique du génome humain, la région intergénique contenant au moins un polymorphisme d'un petit nucléotide (SNP) associé à un(e) ou plusieurs maladies ou troubles humains. L'invention concerne également des procédés pour la détection de ces petites molécules d'ARN non codantes dans un échantillon biologique et des procédés thérapeutiques, diagnostiques et pronostiques associés.
Also published as
Latest bibliographic data on file with the International Bureau