Processing

Please wait...

Settings

Settings

Goto Application

1. WO2011008974 - RSV F PROTEIN COMPOSITIONS AND METHODS FOR MAKING SAME

Publication Number WO/2011/008974
Publication Date 20.01.2011
International Application No. PCT/US2010/042161
International Filing Date 15.07.2010
IPC
A61K 39/155 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
12Viral antigens
155Paramyxoviridae, e.g. parainfluenza virus
C07K 14/135 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
005from viruses
08RNA viruses
115Paramyxoviridae, e.g. parainfluenza virus
135Respiratory syncytial virus
C07K 16/10 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
08against material from viruses
10from RNA viruses
CPC
A61K 2039/5252
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
51comprising whole cells, viruses or DNA/RNA
525Virus
5252inactivated (killed)
A61K 2039/5256
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
51comprising whole cells, viruses or DNA/RNA
525Virus
5256expressing foreign proteins
A61K 2039/5258
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
51comprising whole cells, viruses or DNA/RNA
525Virus
5258Virus-like particles
A61K 2039/53
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
51comprising whole cells, viruses or DNA/RNA
53DNA (RNA) vaccination
A61K 2039/55505
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
555characterised by a specific combination antigen/adjuvant
55505Inorganic adjuvants
A61K 2039/55555
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
555characterised by a specific combination antigen/adjuvant
55511Organic adjuvants
55555Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
Applicants
  • NOVARTIS AG [CH]/[CH] (AllExceptUS)
  • SWANSON, Kurt [US]/[US] (UsOnly)
  • DORMITZER, Philip, R. [US]/[US] (UsOnly)
Inventors
  • SWANSON, Kurt
  • DORMITZER, Philip, R.
Agents
  • LEE, Helen
Priority Data
61/225,80515.07.2009US
61/294,42612.01.2010US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) RSV F PROTEIN COMPOSITIONS AND METHODS FOR MAKING SAME
(FR) COMPOSITIONS À BASE DE PROTÉINE F DU VRS ET PROCÉDÉS DE FABRICATION ASSOCIÉS
Abstract
(EN)
The present invention relates to immunogenic compositions comprising RSV F protein, methods for preparing compositions that contain RSV F protein ecto-domain polypeptides, and to certain engineered RSV F proteins and nucleic acids that encode the engineered RSV F proteins. Compositions prepared using the methods can contain RSV F protein ecto-domain polypeptides in a predominant or single desired form and conformation. The invention also relates to methods for inducing an immune response to RSV F.
(FR)
La présente invention concerne des compositions immunogènes comprenant la protéine F du VRS, des procédés de préparation des compositions qui contiennent des polypeptides de l'ectodomaine de la protéine F du VRS, et certaines protéines F du VRS modifiées et des acides nucléiques qui codent pour les protéines F de VRS modifiées. Les compositions préparées à l'aide des procédés peuvent contenir des polypeptides de l'ectodomaine de la protéine F du VRS sous une forme et une conformation souhaitées prédominantes ou uniques. L'invention concerne également des procédés d'induction d'une réponse immunitaire contre la protéine F du VRS.
Latest bibliographic data on file with the International Bureau