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1. WO2011008904 - COMPOSITIONS AND METHODS FOR GENETIC MODIFICATION OF CELLS HAVING COSMETIC FUNCTION TO ENHANCE COSMETIC APPEARANCE

Publication Number WO/2011/008904
Publication Date 20.01.2011
International Application No. PCT/US2010/042051
International Filing Date 15.07.2010
Chapter 2 Demand Filed 15.02.2011
IPC
C12N 15/09 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
A61K 48/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
48Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
CPC
A61K 48/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
48Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
A61K 48/005
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
48Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
005characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
A61P 17/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17Drugs for dermatological disorders
C07H 21/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
21Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
04with deoxyribosyl as saccharide radical
C07K 14/475
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
475Growth factors; Growth regulators
C12N 15/63
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
Applicants
  • TABOR, Aaron, T. [US]/[US]
  • HARMON, John, Watson [US]/[US]
Inventors
  • TABOR, Aaron, T.
  • HARMON, John, Watson
Agents
  • WEATHERSPOON, John, K.
Priority Data
61/226,51817.07.2009US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) COMPOSITIONS AND METHODS FOR GENETIC MODIFICATION OF CELLS HAVING COSMETIC FUNCTION TO ENHANCE COSMETIC APPEARANCE
(FR) COMPOSITIONS ET PROCÉDÉS POUR LA MODIFICATION GÉNÉTIQUE DE CELLULES AYANT UNE FONCTION COSMÉTIQUE AFIN D'AMÉLIORER L'ASPECT COSMÉTIQUE
Abstract
(EN)
Disclosed are methods and compositions to genetically modify substantially intact cells having cosmetic function to enhance the cosmetic appearance in mammals so as to enhance and/or maintain a biochemical and/or physiological process that has a positive effect on cosmetic appearance. The methods and compositions may provide cosmetic benefits such as reduced skin sagging, increased skin thickness, reduced wrinkles, increased skin thickness and collagen content, increased skin tone and elasticity, increased skin hydration, and improved skin texture and color.
(FR)
L'invention porte sur des procédés et des compositions pour modifier génétiquement des cellules sensiblement intactes ayant une fonction cosmétique afin d'améliorer l'aspect cosmétique chez les mammifères de façon à augmenter et/ou maintenir un processus biochimique et/ou physiologique qui a un effet positif sur l'aspect cosmétique. Les procédés et compositions peuvent fournir des avantages cosmétiques tels qu'une réduction de l'affaissement de la peau, une augmentation de l'épaisseur de la peau, une réduction des rides, une augmentation de l'épaisseur de la peau et une augmentation de la teneur en collagène, une augmentation de la tonicité et de l'élasticité de la peau, une augmentation de l'hydratation de la peau et une amélioration de la texture et de la couleur de la peau.
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