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1. WO2011006161 - COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING MACULAR DEGENERATION

Publication Number WO/2011/006161
Publication Date 13.01.2011
International Application No. PCT/US2010/041720
International Filing Date 12.07.2010
IPC
C12Q 1/68 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
C12N 15/12 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
11DNA or RNA fragments; Modified forms thereof
12Genes encoding animal proteins
C40B 40/08 2006.01
CCHEMISTRY; METALLURGY
40COMBINATORIAL TECHNOLOGY
BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICO LIBRARIES
40Libraries per se, e.g. arrays, mixtures
04Libraries containing only organic compounds
06Libraries containing nucleotides or polynucleotides, or derivatives thereof
08Libraries containing RNA or DNA which encodes proteins, e.g. gene libraries
CPC
C12Q 1/6883
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms
68involving nucleic acids
6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
6883for diseases caused by alterations of genetic material
C12Q 2600/156
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
2600Oligonucleotides characterized by their use
156Polymorphic or mutational markers
C12Q 2600/158
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
2600Oligonucleotides characterized by their use
158Expression markers
C12Q 2600/172
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
2600Oligonucleotides characterized by their use
172Haplotypes
Y10T 436/143333
YSECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
10TECHNICAL SUBJECTS COVERED BY FORMER USPC
TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
436Chemistry: analytical and immunological testing
14Heterocyclic carbon compound [i.e. , O, S, N, Se, Te, as only ring hetero atom]
142222Hetero-O [e.g., ascorbic acid, etc.]
143333Saccharide [e.g., DNA, etc.]
Applicants
  • THE REGENTS OF THE UNIVERSITY OF MICHIGAN [US]/[US] (AllExceptUS)
  • MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH [US]/[US] (AllExceptUS)
  • THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA [US]/[US] (AllExceptUS)
  • SWAROOP, Anand [US]/[US] (UsOnly)
  • ABECASIS, Gonçalo [PT]/[US]
  • CHEN, Wei [CN]/[US]
  • EDWARDS, Albert, O. [US]/[US]
  • STAMBOLIAN, Dwight [US]/[US]
Inventors
  • SWAROOP, Anand
  • ABECASIS, Gonçalo
  • CHEN, Wei
  • EDWARDS, Albert, O.
  • STAMBOLIAN, Dwight
Agents
  • CASIMIR, David, A.
Priority Data
61/224,75310.07.2009US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING MACULAR DEGENERATION
(FR) COMPOSITIONS ET PROCÉDÉS PERMETTANT DE DIAGNOSTIQUER ET DE TRAITER LA DÉGÉNÉRESCENCE MACULAIRE
Abstract
(EN)
The present invention relates generally to biomarkers for macular degeneration. In particular, the present invention provides a plurality of biomarkers for monitoring and diagnosing macular degeneration. The compositions and methods of the present invention find use in diagnostic, therapeutic, research, and drug screening applications.
(FR)
La présente invention concerne en général des biomarqueurs de la dégénérescence maculaire. En particulier, elle concerne une pluralité de biomarqueurs permettant de surveiller et de diagnostiquer la dégénérescence maculaire. Les compositions et les méthodes de la présente invention trouvent une utilisation dans des applications diagnostiques, thérapeutiques, de recherche et de criblage de médicaments.
Also published as
Latest bibliographic data on file with the International Bureau