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1. WO2011006032 - MODULAR SYSTEM FOR RADIOSYNTHESIS WITH MULTI-RUN CAPABILITIES AND REDUCED RISK OF RADIATION EXPOSURE

Publication Number WO/2011/006032
Publication Date 13.01.2011
International Application No. PCT/US2010/041467
International Filing Date 09.07.2010
Chapter 2 Demand Filed 18.11.2011
IPC
B01J 19/00 2006.01
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
19Chemical, physical or physico-chemical processes in general; Their relevant apparatus
B01L 3/00 2006.01
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
3Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
CPC
B01J 19/0093
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
19Chemical, physical or physico-chemical processes in general; Their relevant apparatus
0093Microreactors, e.g. miniaturised or microfabricated reactors
B01J 2219/0081
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
2219Chemical, physical or physico-chemical processes in general; Their relevant apparatus
00781Aspects relating to microreactors
00801Means to assemble
0081Plurality of modules
B01J 2219/00826
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
2219Chemical, physical or physico-chemical processes in general; Their relevant apparatus
00781Aspects relating to microreactors
00819Materials of construction
00824Ceramic
00826Quartz
B01J 2219/0086
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
2219Chemical, physical or physico-chemical processes in general; Their relevant apparatus
00781Aspects relating to microreactors
00851Additional features
00858Aspects relating to the size of the reactor
0086Dimensions of the flow channels
B01J 2219/00871
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
2219Chemical, physical or physico-chemical processes in general; Their relevant apparatus
00781Aspects relating to microreactors
00851Additional features
00871Modular assembly
B01J 2219/00936
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
2219Chemical, physical or physico-chemical processes in general; Their relevant apparatus
00781Aspects relating to microreactors
00925Irradiation
00934Electromagnetic waves
00936UV-radiations
Applicants
  • SIEMENS MEDICAL SOLUTIONS USA, INC. [US]/[US] (AllExceptUS)
  • ELIZAROV, Arkadij M. [US]/[US] (UsOnly)
  • BALL, Carroll Edward [US]/[US] (UsOnly)
  • ZHANG, Jianzhong [US]/[US] (UsOnly)
  • KOLB, Hartmuth C. [DE]/[US] (UsOnly)
  • MIRAGHAIE, Reza [US]/[US] (UsOnly)
  • LEBEDEV, Artem [RU]/[US] (UsOnly)
  • GRAVES, Todd, L. [US]/[US] (UsOnly)
Inventors
  • ELIZAROV, Arkadij M.
  • BALL, Carroll Edward
  • ZHANG, Jianzhong
  • KOLB, Hartmuth C.
  • MIRAGHAIE, Reza
  • LEBEDEV, Artem
  • GRAVES, Todd, L.
Agents
  • RYAN, Joshua B.
  • FRENCH, Clive Harry
Priority Data
12/803,86208.07.2010US
61/224,31109.07.2009US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) MODULAR SYSTEM FOR RADIOSYNTHESIS WITH MULTI-RUN CAPABILITIES AND REDUCED RISK OF RADIATION EXPOSURE
(FR) SYSTÈME MODULAIRE POUR LA RADIOSYNTHÈSE AVEC DES CAPACITÉS DE PASSES MULTIPLES ET UN RISQUE RÉDUIT D'EXPOSITION AUX RAYONNEMENTS
Abstract
(EN)
Macro- and microfluidic devices and related technologies, and chemical processes using such devices. More specifically, the devices may be used for a fully automated synthesis of radioactive compounds for imaging, such as by positron emission tomography (PET), in an efficient, compact and safe to the operator manner. In particular, embodiments of the present invention relate to an automated, multi-run, microfluidic instrument for the multi-step synthesis of radiopharmaceuticals, such as PET probes, comprising a remote shielded mini-cell containing radiation-handing components.
(FR)
L'invention concerne des dispositifs macrofluidiques et microfluidiques et les technologies associées, et les processus chimiques utilisant de tels dispositifs. Plus spécifiquement, les dispositifs peuvent être utilisés pour une synthèse totalement automatisée de composés radioactifs pour l'imagerie, comme la tomographie à émission de positrons (TEP), de manière efficace, compacte et sûre pour l'opérateur. En particulier, des modes de réalisation de la présente invention concernent un instrument microfluidique automatique à passes multiples pour la synthèse en plusieurs étapes de produits radiopharmaceutiques, comme les sondes pour TEP, comprenant une minicellule blindée distante contenant des composants produisant des rayonnements.
Also published as
Latest bibliographic data on file with the International Bureau