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1. WO2011004395 - MICROEMULSION FORMULATION FOR BIOLOGICALS

Publication Number WO/2011/004395
Publication Date 13.01.2011
International Application No. PCT/IN2010/000447
International Filing Date 02.07.2010
IPC
A61K 9/107 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
10Dispersions; Emulsions
107Emulsions
A61K 47/44 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42107; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
A61K 38/26 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17from animals; from humans
22Hormones
26Glucagons
CPC
A61K 38/29
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17from animals; from humans
22Hormones
29Parathyroid hormone (parathormone); Parathyroid hormone-related peptides
A61K 47/14
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
08containing oxygen, ; e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
A61K 9/0095
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
0087Galenical forms not covered by A61K9/02 - A61K9/7023
0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
A61K 9/1075
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
10Dispersions; Emulsions
107Emulsions ; ; Emulsion preconcentrates; Micelles
1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
Applicants
  • INTAS BIOPHARMACEUTICALS LIMITED [IN]/[IN] (AllExceptUS)
  • MODY Rustom Sorab [IN]/[IN] (UsOnly)
  • GUPTA Ajay, Kumar [IN]/[IN] (UsOnly)
  • PAUL Sumita [IN]/[IN] (UsOnly)
Inventors
  • MODY Rustom Sorab
  • GUPTA Ajay, Kumar
  • PAUL Sumita
Agents
  • SANTHANAM Kausalya
Priority Data
1600/MUM/200906.07.2009IN
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) MICROEMULSION FORMULATION FOR BIOLOGICALS
(FR) FORMULATION DE MICROÉMULSION POUR SUBSTANCES BIOLOGIQUES
Abstract
(EN)
The present invention provides a stable water-in-oil microemulsion pharmaceutical formulation comprising a continuous oil phase and a dispersed aqueous phase containing a biological. The microemulsion formulation of the present invention is stable under refrigerated conditions, have acceptable organo-leptic properties and improve the absorption of biologicals through mucous membrane.
(FR)
L'invention concerne une formulation pharmaceutique de microémulsion eau-dans-huile qui comprend une phase huile continue et une phase aqueuse dispersée contenant une substance biologique. Ladite formulation est stable sous en conditions réfrigérées, elle a des propriétés organoleptiques et améliore l'absorption de substances biologiques à travers une membrane muqueuse.
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