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1. WO2011004197 - SCREENING METHOD FOR CELL AGING

Publication Number WO/2011/004197
Publication Date 13.01.2011
International Application No. PCT/GB2010/051128
International Filing Date 08.07.2010
IPC
G01N 33/50 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
CPC
G01N 2440/10
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
2440Post-translational modifications [PTMs] in chemical analysis of biological material
10acylation, e.g. acetylation, formylation, lipoylation, myristoylation, palmitoylation
G01N 2800/00
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
2800Detection or diagnosis of diseases
G01N 33/5008
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
5005involving human or animal cells
5008for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
G01N 33/6872
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68involving proteins, peptides or amino acids
6872Intracellular protein regulatory factors and their receptors, e.g. including ion channels
Applicants
  • CHRONOS THERAPEUTICS LIMITED [GB]/[GB] (AllExceptUS)
  • MELLOR, Elizabeth Jane [GB]/[GB] (UsOnly)
  • YOUDELL, Michael [GB]/[GB] (UsOnly)
  • NAIR, Anita [GB]/[GB] (UsOnly)
  • AKOULITCHEV, Alexandre [GB]/[GB] (UsOnly)
Inventors
  • MELLOR, Elizabeth Jane
  • YOUDELL, Michael
  • NAIR, Anita
  • AKOULITCHEV, Alexandre
Agents
  • BLANCE, Stephen
Priority Data
0911885.208.07.2009GB
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) SCREENING METHOD FOR CELL AGING
(FR) PROCÉDÉ DE DÉPISTAGE POUR LE VIEILLISSEMENT CELLULAIRE
Abstract
(EN)
The present invention relates to a method for increasing the chronological lifespan of a cell comprising disrupting the function of at least one of the SAGA1 SLIK and/or SALSA complexes in said cell.
(FR)
La présente invention concerne un procédé pour augmenter la durée de vie chronologique d'une cellule comprenant la rupture de la fonction d'au moins un parmi les complexes SAGA1 SLIK et/ou SALSA dans ladite cellule.
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