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1. WO2011004016 - PYRIDINE DERIVATIVES WITH UMAMI FLAVOUR

Publication Number WO/2011/004016
Publication Date 13.01.2011
International Application No. PCT/EP2010/059916
International Filing Date 09.07.2010
IPC
C07D 213/50 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
213Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
02having three double bonds between ring members or between ring members and non-ring members
04having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
24with substituted hydrocarbon radicals attached to ring carbon atoms
44Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
46Oxygen atoms
50Ketonic radicals
C07D 405/06 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
405Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
02containing two hetero rings
06linked by a carbon chain containing only aliphatic carbon atoms
A23L 1/226 2006.1
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D91; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
1Foods or foodstuffs; Their preparation or treatment
22Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes
226Synthetic spices or flavouring agents or condiments
CPC
A23L 27/2024
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A23B - A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT
27Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
20Synthetic spices, flavouring agents or condiments
202Aliphatic compounds
2024having oxygen as the only hetero atom
A23L 27/203
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A23B - A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT
27Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
20Synthetic spices, flavouring agents or condiments
203Alicyclic compounds
A23L 27/2052
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A23B - A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT
27Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
20Synthetic spices, flavouring agents or condiments
205Heterocyclic compounds
2052having oxygen or sulfur as the only hetero atoms
A23L 27/2054
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A23B - A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT
27Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
20Synthetic spices, flavouring agents or condiments
205Heterocyclic compounds
2054having nitrogen as the only hetero atom
A23L 27/70
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A23B - A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT
27Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
70Fixation, conservation, or encapsulation of flavouring agents
C07D 213/46
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
213Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
02having three double bonds between ring members or between ring members and non-ring members
04having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
24with substituted hydrocarbon radicals attached to ring carbon atoms
44Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
46Oxygen atoms
Applicants
  • GIVAUDAN SA [CH]/[CH] (AllExceptUS)
  • WANG, Yili [US]/[US] (UsOnly)
  • DANIHER, Andrew [US]/[US] (UsOnly)
  • DE KLERK, Adri [NL]/[NL] (UsOnly)
  • WINKEL, Cornelis [NL]/[NL] (UsOnly)
Inventors
  • WANG, Yili
  • DANIHER, Andrew
  • DE KLERK, Adri
  • WINKEL, Cornelis
Agents
  • MCSTEA, John, Anthony
Priority Data
61/224,60410.07.2009US
61/235,45220.08.2009US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) PYRIDINE DERIVATIVES WITH UMAMI FLAVOUR
(FR) DÉRIVÉS DE LA PYRIDINE AYANT UN GOÛT UMAMI
Abstract
(EN) A compound (including salts thereof) according to Formula I in which R1 is H, methyl or ethyl; R2 is H, OH, fluorine, C1-C4 linear or branched alkyl, C1-C6 alkoxy wherein the alkyl group is linear or branched, or a C3-C5 cycloalkyl moiety; R3 is H, methoxy, methyl or ethyl; or R2 and R3 together form a bridging moiety -O-CH2-O- between the phenyl carbon atoms to which they are connected; R4 is OH or methoxy; and R5 and R6 are independently H or methyl; R1, R2, R3, R4, R5 and R6 are such that, (i) when R2 and R3 together form a bridging moiety -O-CH2-O- between the phenyl carbon atoms to which they are connected, R1, R5, R6 are H, and R4 is OH; and (ii) when R4 is OH and R1-R3 are H, at least one of R5, R6 is methyl.
(FR) La présente invention a pour objet un composé (y compris ses sels) selon la Formule I dans laquelle R1 est H, un méthyle ou un éthyle; R2 est H, OH, le fluor, un alkyle linéaire ou ramifié en C1 à C4, un alcoxy en C1 à C6, le groupe alkyle étant linéaire ou ramifié, ou un groupement cycloalkyle en C3 à C5; R3 est H, un méthoxy, un méthyle ou un éthyle; ou R2 et R3 forment ensemble un groupement pontant -O-CH2-O- entre les atomes de carbone phényliques auxquels ils sont liés; R4 est OH ou un méthoxy; et R5 et R6 sont indépendamment H ou un méthyle; R1, R2, R3, R4, R5 et R6 sont tels que, (i) lorsque R2 et R3 forment ensemble un groupement pontant -O-CH2-O- entre les atomes de carbone phényliques auxquels ils sont liés, R1, R5, R6 soient H, et R4 soit OH; et (ii) lorsque R4 est OH et R1 à R3 sont H, R5 et/ou R6 soient un méthyle.
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