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1. WO2011003035 - ANALYTE SENSOR

Publication Number WO/2011/003035
Publication Date 06.01.2011
International Application No. PCT/US2010/040838
International Filing Date 01.07.2010
IPC
A61B 5/145 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes; Identification of persons
145Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
A61B 5/1468 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes; Identification of persons
145Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
1468using chemical or electrochemical methods, e.g. by polarographic means
CPC
A61B 2560/0223
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
2560Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
02Operational features
0223of calibration, e.g. protocols for calibrating sensors
A61B 2562/0209
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
2562Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
02Details of sensors specially adapted for in-vivo measurements
0209Special features of electrodes classified in A61B5/04001, A61B5/0408, A61B5/042, A61B5/0478, A61B5/0492 or A61B5/053
A61B 2562/043
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
2562Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
04Arrangements of multiple sensors of the same type
043in a linear array
A61B 2562/125
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
2562Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
12Manufacturing methods specially adapted for producing sensors for in-vivo measurements
125characterised by the manufacture of electrodes
A61B 5/14503
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Detecting, measuring or recording for diagnostic purposes
145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
14503invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
A61B 5/1451
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Detecting, measuring or recording for diagnostic purposes
145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
14507specially adapted for measuring characteristics of body fluids other than blood
1451for interstitial fluid
Applicants
  • DEXCOM, INC. [US]/[US] (AllExceptUS)
  • SIMPSON, Peter, C. [US]/[US] (UsOnly)
  • BOOCK, Robert [US]/[US] (UsOnly)
  • KAMATH, Apurv, Ullas [US]/[US] (UsOnly)
  • WIGHTLIN, Matthew [US]/[US] (UsOnly)
  • ESTES, Michael, J. [US]/[US] (UsOnly)
Inventors
  • SIMPSON, Peter, C.
  • BOOCK, Robert
  • KAMATH, Apurv, Ullas
  • WIGHTLIN, Matthew
  • ESTES, Michael, J.
Agents
  • MALLON, Joseph, J.
Priority Data
61/222,71602.07.2009US
61/222,75102.07.2009US
61/222,81502.07.2009US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) ANALYTE SENSOR
(FR) CAPTEUR D'ANALYTES
Abstract
(EN)
Devices and methods are provided for continuous measurement of an analyte concentration. The device can include a sensor having a plurality of sensor elements, each having at least one characteristic that is different from other sensor(s) of the device. In some embodiments, the plurality of sensor elements are each tuned to measure a different range of analyte concentration, thereby providing the device with the capability of achieving a substantially consistent level of measurement accuracy across a physiologically relevant range. In other embodiments, the device includes a plurality of sensor elements each tuned to measure during different time periods after insertion or implantation, thereby providing the sensor with the capability to continuously and accurately measure analyte concentrations across a wide range of time periods. For example, a sensor system (180) is provided having a first working electrode (150) comprising a first sensor element (102) and a second working electrode (160) comprising a second sensor element (104), and a reference electrode (108) for providing a reference value for measuring the working electrode potential of the sensor elements (102, 104).
(FR)
La présente invention concerne des dispositifs et des procédés de mesure en continu d'une concentration d'analytes. Le dispositif peut comprendre un capteur comportant une pluralité d'éléments capteurs, chacun possédant au moins une caractéristique qui est différente de celle du ou des autres capteurs du dispositif. Dans certains modes de réalisation, la pluralité d'éléments capteurs sont chacun ajustés pour mesurer une plage différente de concentrations d'analytes, ce qui donne au dispositif la capacité d'obtenir une précision de mesure présentant un niveau sensiblement cohérent sur une plage physiologiquement pertinente. Dans d'autres modes de réalisation, le dispositif comprend une pluralité d'éléments capteurs qui sont chacun ajustés pour effectuer des mesures pendant des périodes de temps différentes après l'insertion ou l'implantation, ce qui donne au capteur la capacité de mesurer en continu et de façon précise des concentrations d'analytes sur une large plage de périodes de temps. Par exemple, un système capteur (180) comporte une première électrode active (150) comprenant un premier élément capteur (102) et une seconde électrode active (160) comprenant un second élément capteur (104), ainsi qu'une électrode de référence (108) permettant de fournir une valeur de référence pour mesurer le potentiel d'électrode active des éléments capteurs (102, 104).
Also published as
Latest bibliographic data on file with the International Bureau