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Machine translation
1. (WO2010151804) ADMINISTRATION OF DIHYDROERGOTAMINE MESYLATE PARTICLES USING A METERED DOSE INHALER
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/151804    International Application No.:    PCT/US2010/040048
Publication Date: 29.12.2010 International Filing Date: 25.06.2010
IPC:
A01N 43/58 (2006.01)
Applicants: MAP PHARMACEUTICALS, INC. [US/US]; 2400 Bayshore Parkway, Suite 200 Mountain View, CA 94043 (US) (For All Designated States Except US).
KELLERMAN, Donald, J. [US/US]; (US) (For US Only).
KORI, Shashidhar, H. [US/US]; (US) (For US Only).
BORLAND, Scott, W. [US/US]; (US) (For US Only).
ARMER, Thomas, A. [US/US]; (US) (For US Only)
Inventors: KELLERMAN, Donald, J.; (US).
KORI, Shashidhar, H.; (US).
BORLAND, Scott, W.; (US).
ARMER, Thomas, A.; (US)
Agent: MCCRACKEN, Thomas; VP, Intellectual Property MAP Pharmaceuticals, Inc. 2400 Bayshore Parkway, Suite 200 Mountain View, CA 94043 (US)
Priority Data:
61/269,688 26.06.2009 US
Title (EN) ADMINISTRATION OF DIHYDROERGOTAMINE MESYLATE PARTICLES USING A METERED DOSE INHALER
(FR) ADMINISTRATION DE PARTICULES DE DIHYDRO-ERGOTAMINE MÉSYLATE AU MOYEN D'UN INHALATEUR-DOSEUR
Abstract: front page image
(EN)Disclosed are compositions of matter and related methods that provide a metered dose inhaler that includes a formulation having a dose that comprises a hydrofluoroalkane propellant and dihydroergotamine mesylate particles; wherein the dose includes between 0.1 mg to 4 mg of dihydroergotamine mesylate; wherein the dihydroergotamine mesylate particles have a cumulative drug substance particle size distribution with d10 > 0.5 micron volumetric median diameter and d90 < 5.0 micron volumetric median diameter.
(FR)La présente invention concerne des compositions et des procédés de réalisation d'un inhalateur-doseur pouvant débiter une quantité dosée d'une formulation comprenant un propulseur, à savoir l'hydrofluoroalcane, et des particules de dihydro-ergotamine mésylate, à raison de 0,1 mg à 4 mg de dihydro-ergotamine mésylate. En l'occurrence, les particules de dihydro-ergotamine mésylate présente une distribution cumulée des dimensions des particules de la substance médicamenteuse présentant un diamètre volumétrique médian d10 > 0,5 µm et un diamètre volumétrique médian d90 < 0,5 µm.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)