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1. (WO2010151755) TREATMENT OF INFLAMMATORY DISEASES USING miR-124
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/151755    International Application No.:    PCT/US2010/039974
Publication Date: 29.12.2010 International Filing Date: 25.06.2010
IPC:
A61K 38/16 (2006.01), A61P 25/28 (2006.01), A61P 3/10 (2006.01), A61P 25/00 (2006.01)
Applicants: THE BRIGHAM AND WOMEN'S HOSPITAL, INC. [US/US]; 75 Francis Street Boston, Massachusetts 02115 (US) (For All Designated States Except US).
WEINER, Howard [US/US]; (US) (For US Only).
PONOMAREV, Eugene [RU/US]; (US) (For US Only).
VEREMEYKO, Tatyana [RU/US]; (US) (For US Only).
KRICHEVSKY, Anna M. [US/US]; (US) (For US Only)
Inventors: WEINER, Howard; (US).
PONOMAREV, Eugene; (US).
VEREMEYKO, Tatyana; (US).
KRICHEVSKY, Anna M.; (US)
Agent: DEYOUNG, Janice Kugler; Fish & Richardson P.C. P.O. Box 1022 Minneapolis, Minnesota 55440-1022 (US)
Priority Data:
61/220,281 25.06.2009 US
Title (EN) TREATMENT OF INFLAMMATORY DISEASES USING miR-124
(FR) TRAITEMENT DE MALADIES INFLAMMATOIRES À L'AIDE DU MICROARN MIR-124
Abstract: front page image
(EN)Methods of treating, reducing the risk of developing, or delaying the onset of an inflammatory disease are disclosed. The methods involved providing a subject with or at risk of developing an inflammatory disease and administering to the subject an effective amount of a first therapeutic composition comprising miR-124. Further provided are methods of diagnosing a subject with or at risk of developing an inflammatory disease.
(FR)La présente invention concerne des procédés de traitement, de diminution du risque ou de retard de l'apparition d'une maladie inflammatoire. Les procédés consistent à identifier un sujet présentant une maladie inflammatoire ou un risque de développer une telle maladie et à lui administrer une quantité efficace d'une première composition thérapeutique comprenant le microARN miR-124. La présente invention concerne, en outre, des procédés de diagnostic d'un sujet présentant ou non un risque de développer une maladie inflammatoire.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)