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1. (WO2010151710) SUBSTITUTED HETEROCYCLIC COMPOUNDS AS KINASES INHIBITORS AND METHOD OF USE THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/151710    International Application No.:    PCT/US2010/039877
Publication Date: 29.12.2010 International Filing Date: 24.06.2010
IPC:
C07D 215/227 (2006.01), C07D 401/12 (2006.01), C07D 239/94 (2006.01), A61K 31/517 (2006.01), A61P 35/00 (2006.01)
Applicants: MEDOLUTION LIMITED [CN/CN]; Room 1105, Lippo Center Tower 1, 89 Queensway Admiralty (HK) (For All Designated States Except US).
ZHANG, Dawei [US/US]; (US) (For US Only)
Inventors: ZHANG, Dawei; (US)
Agent: LIANG, C.,Jason; Wilson Sonsini Goodrich & Rosati 650 Page Mill Road Palo Alto, CA 94304-1050 (US)
Priority Data:
61/269,525 25.06.2009 US
Title (EN) SUBSTITUTED HETEROCYCLIC COMPOUNDS AS KINASES INHIBITORS AND METHOD OF USE THEREOF
(FR) COMPOSÉS HÉTÉROCYCLIQUES SUBSTITUÉS UTILISÉS EN TANT QU'INHIBITEURS DE LA KINASE ET LEUR PROCÉDÉ D'UTILISATION
Abstract: front page image
(EN)The present invention is directed to novel quinolines and quniazolines, their derivatives, pharmaceutically acceptable salts, solvates and hydrates thereof which are useful for the treatment of protein kinases mediated diseases and conditions. The compounds of this invention have a general Formula (I) wherein R1 to R11 and X are defined herein.
(FR)La présente invention concerne des nouvelles quinoléines et quinazolines, leurs dérivés ainsi que leurs sels, produits de solvatation et hydrates pharmaceutiquement acceptables, qui sont utiles dans le traitement des maladies initiées par les protéines kinases. Les composés selon la présente invention sont représentés par la formule générale (I) dans laquelle R1 à R11 et X sont tels que définis dans les présentes.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)