WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2010151426) TRUNCATED ACTRIIB-FC FUSION PROTEINS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/151426    International Application No.:    PCT/US2010/037787
Publication Date: 29.12.2010 International Filing Date: 08.06.2010
IPC:
C07K 14/705 (2006.01), A61K 38/17 (2006.01), A61P 3/00 (2006.01)
Applicants: ACCELERON PHARMA INC. [US/US]; 128 Sidney Street Cambridge, MA 02139 (US) (For All Designated States Except US).
KNOPF, John [US/US]; (US) (For US Only).
SEEHRA, Jasbir [US/US]; (US) (For US Only).
KUMAR, Ravindra [US/US]; (US) (For US Only)
Inventors: KNOPF, John; (US).
SEEHRA, Jasbir; (US).
KUMAR, Ravindra; (US)
Agent: WARMA, Anita; Ropes & Gray LLP Prudential Tower 800 Boylston Street Boston, MA 02199-3600 (US)
Priority Data:
61/276,422 10.09.2009 US (Priority Withdrawn 10.10.2010)
61/268,128 08.06.2009 US (Priority Withdrawn 10.10.2010)
61/280,545 03.11.2009 US (Priority Withdrawn 10.10.2010)
61/268,420 12.06.2009 US
61/280,543 03.11.2009 US
Title (EN) TRUNCATED ACTRIIB-FC FUSION PROTEINS
(FR) PROTÉINES DE FUSION ACTRIIB-FC TRONQUÉES
Abstract: front page image
(EN)In certain aspects, the present invention provides compositions comprising polypeptides that are derived from ActRIIB for modulating (promoting or inhibiting) growth of a tissue, such as bone, cartilage, muscle, fat, brown fat and/or neuronal tissue and for treating metabolic disorders such as diabetes and obesity, as well as dis'orders associated with any of the foregoing tissue.
(FR)La présente invention concerne, selon certains aspects, des compositions comprenant des polypeptides qui sont dérivés d'ActRIIB pour la modulation (promotion ou inhibition) de la croissance d'un tissu, tel qu'un os, un cartilage, un muscle, un tissu adipeux, un tissu adipeux brun et/ou un tissu neuronal et pour le traitement de troubles métaboliques tels que le diabète et l'obésité, ainsi que de troubles associés avec l'un quelconque des tissus précédents.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)