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Machine translation
1. (WO2010149360) PROCESS FOR THE PREPARATION OF BENZIMIDAZOLES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/149360    International Application No.:    PCT/EP2010/003788
Publication Date: 29.12.2010 International Filing Date: 24.06.2010
IPC:
C07D 235/08 (2006.01), C07C 255/50 (2006.01)
Applicants: LONZA LTD [CH/CH]; Münchensteinerstrasse 38 CH-4052 Basel (CH) (For All Designated States Except US).
HANSELMANN, Paul [CH/CH]; (CH) (For US Only).
WONG, Heilam [CN/CN]; (CN) (For US Only).
KLEGRAF, Ellen [DE/CH]; (CH) (For US Only).
ZARAGOZA DÖRWALD, Florencio [DE/CH]; (CH) (For US Only).
DING, Zunliang [CN/CN]; (CN) (For US Only).
LONG, Jun [CN/CN]; (CN) (For US Only)
Inventors: HANSELMANN, Paul; (CH).
WONG, Heilam; (CN).
KLEGRAF, Ellen; (CH).
ZARAGOZA DÖRWALD, Florencio; (CH).
DING, Zunliang; (CN).
LONG, Jun; (CN)
Common
Representative:
LONZA LTD [CH/CH]; Münchensteinerstrasse 38 Ch-4052 Basel (CH)
Priority Data:
09008394.0 26.06.2009 EP
09010391.2 12.08.2009 EP
Title (EN) PROCESS FOR THE PREPARATION OF BENZIMIDAZOLES
(FR) PROCÉDÉ POUR LA PRÉPARATION DE BENZIMIDAZOLES
Abstract: front page image
(EN)Substituted benzimidazoles of formula (I), wherein R1 and R2 independently are hydrogen, C1-6 alkyl or C3-6 cycloalkyl and R3 is cyano or carboxy, are prepared in a multistep synthesis starting from Ν-acyl-4-halo- anilines of formula (II), wherein R1 and R2 are as defined above and X is chlorine or bromine.
(FR)Des benzimidazoles substitués de formule (I), dans laquelle R1 et R2 représentent indépendamment hydrogène, alkyle en C1-6 ou cycloalkyle en C3-6 et R3 représente cyano ou carboxy, sont préparés dans une synthèse en plusieurs étapes à partir de N-acyl-4-haloanilines de formule (II), dans laquelle R1 et R2 sont tels que définis ci-dessus et X représente chlore ou brome.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)