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1. (WO2010148631) DIHYDROPYRIMIDINE COMPOUNDS AND PREPARATION METHODS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/148631    International Application No.:    PCT/CN2010/000757
Publication Date: 29.12.2010 International Filing Date: 27.05.2010
IPC:
C07D 239/20 (2006.01), C07D 401/06 (2006.01), C07D 401/14 (2006.01), C07D 403/06 (2006.01), A61K 31/505 (2006.01), A61K 31/506 (2006.01), A61P 31/12 (2006.01)
Applicants: INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P.L.A. CHINA [CN/CN]; No. 27, Taiping Road Haidian District Beijing 100850 (CN) (For All Designated States Except US).
LI, Song [CN/CN]; (CN) (For US Only).
XU, Xiaoqian [CN/CN]; (CN) (For US Only).
ZHAO, Guoming [CN/CN]; (CN) (For US Only).
WANG, Lili [CN/CN]; (CN) (For US Only).
GUAN, Hua [CN/CN]; (CN) (For US Only).
XIAO, Junhai [CN/CN]; (CN) (For US Only).
ZHONG, Wu [CN/CN]; (CN) (For US Only).
ZHENG, Zhibing [CN/CN]; (CN) (For US Only).
XIE, Yunde [CN/CN]; (CN) (For US Only).
LI, Xingzhou [CN/CN]; (CN) (For US Only).
WANG,Xiaokui [CN/CN]; (CN) (For US Only).
ZHOU, Xinbo [CN/CN]; (CN) (For US Only).
LIU, Hongying [CN/CN]; (CN) (For US Only)
Inventors: LI, Song; (CN).
XU, Xiaoqian; (CN).
ZHAO, Guoming; (CN).
WANG, Lili; (CN).
GUAN, Hua; (CN).
XIAO, Junhai; (CN).
ZHONG, Wu; (CN).
ZHENG, Zhibing; (CN).
XIE, Yunde; (CN).
LI, Xingzhou; (CN).
WANG,Xiaokui; (CN).
ZHOU, Xinbo; (CN).
LIU, Hongying; (CN)
Agent: CCPIT PATENT & TRADEMARK LAW OFFICE; 8th Floor, Vantone New World Plaza 2 Fuchengmenwai Street Beijing 100037 (CN)
Priority Data:
200910148630.2 25.06.2009 CN
Title (EN) DIHYDROPYRIMIDINE COMPOUNDS AND PREPARATION METHODS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF
(FR) COMPOSÉS DE DIHYDROPYRIMIDINE ET LEURS PROCÉDÉS DE PRÉPARATION, LEURS COMPOSITIONS PHARMACEUTIQUES ET LEURS UTILISATIONS
(ZH) 二氢嘧啶类化合物及其制备方法、药物组合物和用途
Abstract: front page image
(EN)Disclosed are dihydropyrimidine compounds and preparation methods, pharmaceutical compositions and uses thereof. Specifically, the compounds shown in general formula (I) or their isomers, or salts or hydrates for medicinal purpose thereof are provided, wherein each variable is defined as in the description. Also disclosed are preparation methods for the compounds shown in general formula (I), and pharmaceutical uses of the compounds shown in general formula (I) and isomers, salts or hydrates for medicinal purpose thereof, in particular, pharmaceutical uses for treating and/or preventing hepatitis B.
(FR)L'invention porte sur des composés de dihydropyrimidine et sur leurs procédés de préparation, leurs compositions pharmaceutiques et leurs utilisations. Plus particulièrement, l'invention porte sur des composés représentés par la formule générale (I) et des isomères, des sels à usage médicinal ou des hydrates de ceux-ci, chaque variable étant telle que définie dans la description. L'invention porte également sur des procédés de préparation des composés représentés par la formule générale (I) et sur des utilisations pharmaceutiques des composés représentés par la formule générale (I) et des isomères, des sels à usage médicinal ou des hydrates de ceux-ci, en particulier sur les utilisations pharmaceutiques destinées à guérir et/ou à prévenir une affection par le virus de l'hépatite B.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)