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1. (WO2010148013) LIPID FORMULATED DSRNA TARGETING THE PCSK9 GENE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/148013    International Application No.:    PCT/US2010/038707
Publication Date: 23.12.2010 International Filing Date: 15.06.2010
IPC:
A61K 9/127 (2006.01), C12N 15/11 (2006.01)
Applicants: ALNYLAM PHARMACEUTICALS, INC. [US/US]; 300 Third Street, Third Floor Cambridge, MA 02142 (US) (For All Designated States Except US).
FITZGERALD, Kevin [US/US]; (US) (For US Only).
HINKLE, Gregory [US/US]; (US) (For US Only).
AKINC, Akin [US/US]; (US) (For US Only).
MILSTEIN, Stuart [US/US]; (US) (For US Only)
Inventors: FITZGERALD, Kevin; (US).
HINKLE, Gregory; (US).
AKINC, Akin; (US).
MILSTEIN, Stuart; (US)
Agent: SHUSTER, Michael, J.; Fenwick & West LLP Silicon Valley Center 801 California Street Mountain View, CA 94041 (US)
Priority Data:
61/293,474 08.01.2010 US
61/187,169 15.06.2009 US
61/244,790 22.09.2009 US
61/285,598 11.12.2009 US
61/313,578 12.03.2010 US
61/218,350 18.06.2009 US
Title (EN) LIPID FORMULATED DSRNA TARGETING THE PCSK9 GENE
(FR) ARN DOUBLE BRIN EN FORMULATION LIPIDIQUE CIBLANT LE GÈNE PCSK9
Abstract: front page image
(EN)This invention relates to composition and methods using lipid formulated siRNA targeted to a PCSK9 gene.
(FR)Cette invention porte sur une composition et des procédés utilisant de l'ARNsi en formulation lipidique ciblé vers un gène PCSK9.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)