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1. (WO2010147973) GAMMA SECRETASE MODULATORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/147973    International Application No.:    PCT/US2010/038655
Publication Date: 23.12.2010 International Filing Date: 15.06.2010
IPC:
C07D 471/04 (2006.01), A61K 31/437 (2006.01), A61P 25/28 (2006.01)
Applicants: SCHERING CORPORATION [US/US]; 2000 Galloping Hill Road Kenilworth, New Jersey 07033 (US) (For All Designated States Except US).
HUANG, Xianhai [CN/US]; (US) (For US Only).
ZHU, Zhaoning [US/US]; (US) (For US Only).
GREENLEE, William, J. [US/US]; (US) (For US Only).
PALANI, Anandan [US/US]; (US) (For US Only).
ASLANIAN, Robert, G. [US/US]; (US) (For US Only)
Inventors: HUANG, Xianhai; (US).
ZHU, Zhaoning; (US).
GREENLEE, William, J.; (US).
PALANI, Anandan; (US).
ASLANIAN, Robert, G.; (US)
Agent: HESS, Susan; Merck & Co., Inc. 126 East Lincoln Avenue Rahway, NJ 07065 (US)
Priority Data:
61/187,456 16.06.2009 US
Title (EN) GAMMA SECRETASE MODULATORS
(FR) MODULATEURS DE GAMMA SÉCRÉTASE
Abstract: front page image
(EN)This invention provides novel compounds that are modulators of gamma secretase. The compounds have the Formula I: Also disclosed are methods of modulating gamma secretase activity and methods of treating Alzheimer's Disease using the compounds of Formula I.
(FR)Cette invention porte sur de nouveaux composés qui sont des modulateurs de la gamma sécrétase. Les composés ont la formule I:. L'invention porte également sur des procédés de modulation de l'activité gamma sécrétase et sur des procédés de traitement de la maladie d'Alzheimer à l'aide des composés de formule I.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)