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Machine translation
1. (WO2010147805) DRUG COATED BALLOON CATHETER AND PHARMACOKINETIC PROFILE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/147805    International Application No.:    PCT/US2010/037799
Publication Date: 23.12.2010 International Filing Date: 08.06.2010
IPC:
A61L 29/14 (2006.01), A61L 29/16 (2006.01)
Applicants: ABBOTT CARDIOVASCULAR SYSTEMS INC. [US/US]; 3200 Lakeside Drive Santa Clara, CA 95054-2807 (US) (For All Designated States Except US).
STANKUS, John, J. [US/US]; (US) (For US Only).
TROLLSAS, Mikael [SE/US]; (US) (For US Only).
HOSSAINY, Syed [US/US]; (US) (For US Only).
ZHANG, Liangxuan [CA/US]; (US) (For US Only).
BERGER, Ed [US/US]; (US) (For US Only).
PACETTI, Stephen, D. [US/US]; (US) (For US Only).
TONER, John, L. [US/US]; (US) (For US Only)
Inventors: STANKUS, John, J.; (US).
TROLLSAS, Mikael; (US).
HOSSAINY, Syed; (US).
ZHANG, Liangxuan; (US).
BERGER, Ed; (US).
PACETTI, Stephen, D.; (US).
TONER, John, L.; (US)
Agent: HULSEBERG, Daniel, J.; Baker Botts LLP 30 Rockefeller Plaza New York, NY 10112-4498 (US)
Priority Data:
12/486,652 17.06.2009 US
Title (EN) DRUG COATED BALLOON CATHETER AND PHARMACOKINETIC PROFILE
(FR) CATHÉTER À BALLONNET REVÊTU DE MÉDICAMENT ET PROFIL PHARMACOCINÉTIQUE
Abstract: front page image
(EN)A drug delivery balloon is provided comprising a balloon having a surface, and a coating disposed on at least a portion of the balloon surface, the coating including an cytostatic therapeutic agent, an excipient, and a plasticizer. In accordance with the present subject matter, at least 30% of the coating transfers from the balloon surface within two minutes after inflation of the balloon. Alternatively, at least 30% of the coating transfers from the balloon surface within one minute after inflation. The coating results in an effective pharmacokinetic profile of an cytostatic therapeutic agent in a vasculature or target tissue.
(FR)L'invention porte sur un ballonnet d'administration de médicament comprenant un ballonnet ayant une surface et un revêtement disposé sur au moins une partie de la surface de ballonnet, le revêtement comprenant un agent thérapeutique cytostatique, un excipient et un plastifiant. Conformément à la présente invention, au moins 30 % du revêtement se transfère à partir de la surface de ballonnet en l'espace de deux minutes après gonflement du ballonnet. En variante, au moins 30 % du revêtement se transfère à partir de la surface de ballonnet en l'espace d'une minute après gonflement. Le revêtement conduit à un profil pharmacocinétique efficace d'un agent thérapeutique cytostatique dans une vasculature ou un tissu cible.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)