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1. (WO2010147472) INHIBITION OF NFK-B MEDIATED VIRUS REPLICATION WITH SPECIFIC OLIGOSACCHARIDES
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2010/147472 International Application No.: PCT/NL2010/050380
Publication Date: 23.12.2010 International Filing Date: 21.06.2010
Chapter 2 Demand Filed: 27.01.2011
IPC:
A61P 31/12 (2006.01) ,A23L 1/308 (2006.01) ,A61K 31/7004 (2006.01) ,A61K 31/716 (2006.01) ,A61K 31/732 (2006.01)
Applicants: VAN NORREN, Klaske[NL/NL]; NL (UsOnly)
DIJK, Francina Jeannette[NL/NL]; NL (UsOnly)
BERKHOUT, Benjamin[NL/NL]; NL (UsOnly)
VAN 'T LAND POTAPPEL, Belinda[NL/NL]; NL (UsOnly)
N.V. NUTRICIA[NL/NL]; Eerste Stationsstraat 186 NL-2712 HM Zoetermeer, NL (AllExceptUS)
Inventors: VAN NORREN, Klaske; NL
DIJK, Francina Jeannette; NL
BERKHOUT, Benjamin; NL
VAN 'T LAND POTAPPEL, Belinda; NL
Agent: KETELAARS, Maarten; J.W. Frisolaan 13 NL-2517 JS The Hague, NL
Priority Data:
PCT/NL2009/05036319.06.2009NL
Title (EN) INHIBITION OF NFK-B MEDIATED VIRUS REPLICATION WITH SPECIFIC OLIGOSACCHARIDES
(FR) INHIBITION DE RÉPLICATION DE VIRUS À MÉDIATION PAR NFK-B PAR DES OLIGOSACCHARIDES SPÉCIFIQUES
Abstract:
(EN) The inventors surprisingly found that specific oligosaccharides are capable of inhibiting viral replication through inhibiting NF-κB activation. The invention thus pertains to a composition comprising pectin (in the form of digalacturonic acid, trigalacturonic acid, polygalacturonic acid), Arabinoxylan from rice bran, β-glucan from bakers yeast, D-Ribose or mixtures thereof for inhibiting viral replication in a mammal with a viral disease.
(FR) Les inventeurs ont trouvé de façon surprenante que des oligosaccharides spécifiques sont capables d'inhiber la réplication virale par inhibition de l'activation de NFK-B. L'invention porte donc sur une composition comprenant de la peptine (sous la forme d'acide digalacturonique, d'acide trigalacturonique, d'acide polygalacturonique), d'arabinoxylane provenant de son de riz, de β-glucane provenant de levure de boulanger, de D-ribose ou de mélanges de ceux-ci pour inhiber la réplication virale chez un mammifère atteinte d'une maladie virale.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)