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1. (WO2010145203) 1,2,4-OXADIAZOL DERIVATIVES, THEIR PHARMACEUTICAL COMPOSITIONS AND THEIR USE AS SPHINGOSINE 1-PHOSPHATE 1 RECEPTOR AGONISTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/145203    International Application No.:    PCT/CN2010/000869
Publication Date: 23.12.2010 International Filing Date: 17.06.2010
IPC:
C07D 413/04 (2006.01), C07D 413/14 (2006.01), A61K 31/4245 (2006.01), A61P 37/00 (2006.01)
Applicants: GLAXO GROUP LIMITED [GB/GB]; Glaxo Wellcome House Berkeley Avenue Greenford Middlesex UB6 0NN (GB) (For All Designated States Except US).
LIN, Xichen [US/CN]; (CN) (For US Only).
REN, Feng [CN/CN]; (CN) (For US Only).
SI, Yugui [CN/CN]; (CN) (For US Only)
Inventors: LIN, Xichen; (CN).
REN, Feng; (CN).
SI, Yugui; (CN)
Agent: CHINA PATENT AGENT (H. K.) LTD.; 22/F, Great Eagle Centre 23 Harbour Road Wanchai Hong Kong Special Administrative Region (CN)
Priority Data:
0910667.5 19.06.2009 GB
Title (EN) 1,2,4-OXADIAZOL DERIVATIVES, THEIR PHARMACEUTICAL COMPOSITIONS AND THEIR USE AS SPHINGOSINE 1-PHOSPHATE 1 RECEPTOR AGONISTS
(FR) DÉRIVÉS DE 1,2,4-OXADIAZOLE, LEURS COMPOSITIONS PHARMACEUTIQUES ET LEUR UTILISATION EN TANT QU'AGONISTES DU RÉCEPTEUR 1 DU SPHINGOSINE-1-PHOSPHATE
Abstract: front page image
(EN)1,2,4-Oxadiazol derivatives represented by formula (I) useful as sphingosine 1-phosphate 1 (S1P1) receptor agonists, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders mediated via S1P1 receptor are disclosed.
(FR)La présente invention concerne des dérivés de 1,2,4-oxadiazole représentés par la formule (I) utiles en tant qu'agonistes du récepteur sphingosine-1-phosphate 1 (S1P1), des procédés pour les préparer, des compositions pharmaceutiques les contenant et leur utilisation dans le traitement de diverses affections médiées par le récepteur S1P1.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)