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1. WO2010144734 - BENZONAPHTHYRIDINE-CONTAINING VACCINES

Publication Number WO/2010/144734
Publication Date 16.12.2010
International Application No. PCT/US2010/038216
International Filing Date 10.06.2010
IPC
A61K 39/39 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
39characterised by the immunostimulating additives, e.g. chemical adjuvants
CPC
A61K 2039/55511
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
555characterised by a specific combination antigen/adjuvant
55511Organic adjuvants
A61K 2039/6093
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
60characteristics by the carrier linked to the antigen
6093Synthetic polymers, e.g. polyethyleneglycol [PEG], Polymers or copolymers of (D) glutamate and (D) lysine
A61K 39/39
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
39characterised by the immunostimulating additives, e.g. chemical adjuvants
A61P 31/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
04Antibacterial agents
A61P 31/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
10Antimycotics
A61P 31/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
Applicants
  • NOVARTIS AG [CH]/[CH] (AllExceptUS)
  • O'HAGAN, Derek, T. [US]/[US] (UsOnly)
  • SINGH, Manmohan [US]/[US] (UsOnly)
  • JAIN, Siddhartha [IN]/[US] (UsOnly)
  • KOMMAREDDY, Sushma [IN]/[US] (UsOnly)
Inventors
  • O'HAGAN, Derek, T.
  • SINGH, Manmohan
  • JAIN, Siddhartha
  • KOMMAREDDY, Sushma
Agents
  • Bonham, David, B.
Priority Data
61/185,95410.06.2009US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) BENZONAPHTHYRIDINE-CONTAINING VACCINES
(FR) VACCINS CONTENANT DE LA BENZONAPHTYRIDINE
Abstract
(EN)
The invention provides, inter alia, immunogenic compositions that comprise (a) a first antigen, (b) polymeric particles and (c) a benzonaphthyridine compound, which compositions elicits an immune response when administered to a vertebrate subject. The invention also provides, inter alia, methods of producing immunogenic compositions and methods for using immunogenic compositions (e.g., for treatment), among other benefits.
(FR)
L'invention porte, entre autres, sur des compositions immunogènes qui comprennent (a) un premier antigène, (b) des particules polymères et (c) un composé benzonaphtyridine, lesquelles compositions déclenchent une réponse immunitaire lorsqu'elles sont administrées à un sujet vertébré. L'invention porte également, entre autres, sur des procédés de production de compositions immunogènes et sur des procédés d'utilisation de compositions immunogènes (par exemple, pour un traitement), parmi d'autres avantages.
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