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Machine translation
1. (WO2010144683) COMPOSITIONS AND METHODS FOR DEHYDRATED STORAGE OF ON-BOARD REAGENTS IN MICROFLUIDIC DEVICES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/144683    International Application No.:    PCT/US2010/038141
Publication Date: 16.12.2010 International Filing Date: 10.06.2010
IPC:
C12Q 1/68 (2006.01)
Applicants: MICRONICS, INC. [US/US]; 8463 - 154th Avenue Northeast Redmond, Washington 98052 (US) (For All Designated States Except US).
BATTRELL, C., Frederick [US/US]; (US) (For US Only).
HOEKSTRA, Denise Maxine [US/US]; (US) (For US Only).
HAAB, Joan [US/US]; (US) (For US Only).
WILLIFORD, John R. [US/US]; (US) (For US Only).
GATES, Sabrina N. [US/US]; (US) (For US Only).
LEBER, Elizabeth R. [US/US]; (US) (For US Only).
SPRAGUE, Isaac [US/US]; (US) (For US Only)
Inventors: BATTRELL, C., Frederick; (US).
HOEKSTRA, Denise Maxine; (US).
HAAB, Joan; (US).
WILLIFORD, John R.; (US).
GATES, Sabrina N.; (US).
LEBER, Elizabeth R.; (US).
SPRAGUE, Isaac; (US)
Agent: WAGNER, Emily W.; Seed Intellectual Property Law Group PLLC Suite 5400 701 Fifth Avenue Seattle, Washington 98104-7064 (US)
Priority Data:
61/186,442 12.06.2009 US
Title (EN) COMPOSITIONS AND METHODS FOR DEHYDRATED STORAGE OF ON-BOARD REAGENTS IN MICROFLUIDIC DEVICES
(FR) COMPOSITIONS ET PROCÉDÉS POUR LE STOCKAGE À L'ÉTAT DÉSHYDRATÉ DE RÉACTIFS SUR PUCE DANS DES DISPOSITIFS MICROFLUIDIQUES
Abstract: front page image
(EN)Manufacturing methods and compositions are described for production of self-contained microfluidic cartridge devices with on-board reagents for molecular biological testing. Sensitive reagents are stored in dry form without lyophilization or freezing, and reconstituted at the point of use with either a biological sample or a sample eluate at the point of use. Manufacturing methods include sheet and roll fabrication processes where the reagents are printed in place and sealed within individual microfluidic cartridges before gel vitrification.
(FR)La présente invention concerne des procédés de fabrication et des compositions pour la production de dispositifs de cartouches microfluidiques intégrés dotés de réactifs sur puce pour des essais biologiques moléculaires. Des réactifs sensibles sont stockés sous forme desséchée sans lyophilisation ni congélation, et reconstitués au moment de leur utilisation avec soit un échantillon biologique, soit un échantillon d'éluat au moment de l'utilisation. Les procédés de fabrication comprennent des procédés de fabrication de feuilles et de rouleaux, les réactifs étant imprimés sur place et scellés au sein de cartouches microfluidiques individuelles avant vitrification sur gel.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)