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1. (WO2010144295) APTAMER-TARGETED COSTIMULATORY LIGAND APTAMER
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/144295    International Application No.:    PCT/US2010/037164
Publication Date: 16.12.2010 International Filing Date: 03.06.2010
IPC:
A61K 39/00 (2006.01), A61K 48/00 (2006.01)
Applicants: UNIVERSITY OF MIAMI [US/US]; 1475 N.w. 12th Avenue, Suite 2012 Miami, FL 33136 (US) (For All Designated States Except US).
GILBOA, Eli [US/US]; (US) (For US Only).
PASTOR, Fernando [US/US]; (US) (For US Only)
Inventors: GILBOA, Eli; (US).
PASTOR, Fernando; (US)
Agent: ZACHARIADES, Nicholas; Novak Druce + Quigg LLP 525 Okeechobee Blvd. 15th Floor West Palm Beach, FL 33401 (US)
Priority Data:
61/185,251 09.06.2009 US
Title (EN) APTAMER-TARGETED COSTIMULATORY LIGAND APTAMER
(FR) APTAMÈRE LIGAND CO-STIMULATEUR CIBLÉ PAR UN APTAMÈRE
Abstract: front page image
(EN)Compositions for inducing or enhancing immunogenicity of a tumor comprise bi- and multi-specific aptamers binding to a tumor cell and an immune cell. These compositions have broad applicability in the treatment of many diseases, including cancer.
(FR)L'invention concerne des compositions destinées à induire ou augmenter l'immunogénicité d'une tumeur et comprenant des aptamères bi- et multispécifiques se liant à une cellule tumorale et à une cellule immunitaire. Ces compositions ont de larges applications dans le traitement de nombreuses maladies, notamment le cancer.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)