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1. (WO2010143986) COMBINED THERAPY OF COLORECTAL CARCINOMA
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/143986    International Application No.:    PCT/PL2010/000044
Publication Date: 16.12.2010 International Filing Date: 09.06.2010
IPC:
A61K 31/593 (2006.01), A61K 31/7068 (2006.01)
Applicants: INSTYTUT FARMACEUTYCZNY [PL/PL]; ul. Rydygiera 8 PL-01-793 Warsawa (PL) (For All Designated States Except US).
WIETRZYK, Joanna [PL/PL]; (PL) (For US Only).
MILCZAREK, Magdalena [PL/PL]; (PL) (For US Only).
KUTNER, Andrzej [PL/PL]; (PL) (For US Only).
CHODYŃSKI, Michał [PL/PL]; (PL) (For US Only)
Inventors: WIETRZYK, Joanna; (PL).
MILCZAREK, Magdalena; (PL).
KUTNER, Andrzej; (PL).
CHODYŃSKI, Michał; (PL)
Agent: KRZYWDZIŃSKA, Ewa; Inastytut Farmaceutyczny ul. Rydygiera 8 PL-01-793 Warszawa (PL)
Priority Data:
P-388252 10.06.2009 PL
Title (EN) COMBINED THERAPY OF COLORECTAL CARCINOMA
(FR) THÉRAPIE COMBINÉE DU CANCER COLORECTAL
Abstract: front page image
(EN)The invention relates to a combined therapy, wherein addition of a vitamin D analogue to the standard treatment regimen based on cytostatics, 5-fluorouracil and/or its precursors, generates potential possibility of achieving beneficial therapeutic effect in the first-line chemotherapy or adjuvant therapy of colorectal carcinoma. Vitamin D analogues are selected from a group consisting of tacalcitol, calcipotriol and 5,6-trans-isomer of calcipotriol.
(FR)L'invention concerne une thérapie combinée, l'ajout d'un analogue de vitamine D au régime de traitement standard à base de cytostatiques, de 5-fluorouracil et/ou ses précurseurs créant la possibilité potentielle d'obtenir un effet thérapeutique bénéfique dans une chimiothérapie de première intention ou une thérapie adjuvante du cancer colorectal. Les analogues de vitamine D sont choisis dans un groupe constitué du tacalcitol, du calcipotriol et de l'isomère 5,6-trans du calcipotriol.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)