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1. (WO2010143063) COMPOSITIONS AND METHODS FOR PREVENTION AND TREATMENT OF BRAIN DISEASES AND CONDITIONS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/143063    International Application No.:    PCT/IB2010/001418
Publication Date: 16.12.2010 International Filing Date: 11.06.2010
IPC:
A61K 36/73 (2006.01), A61P 25/28 (2006.01), A61P 25/16 (2006.01)
Applicants: GENEREX PHARMACEUTICALS, INC. [--/CN]; 22nd Floor, Hang Lung Centre 2-20 Paterson Street, Causeway Bay (HK) (For All Designated States Except US).
LI, Ming; (HK) (For US Only).
ZHOU, Zhen [US/CN]; (CN) (For US Only)
Inventors: LI, Ming; (HK).
ZHOU, Zhen; (CN)
Priority Data:
61/186,709 12.06.2009 US
61/187,905 17.06.2009 US
Title (EN) COMPOSITIONS AND METHODS FOR PREVENTION AND TREATMENT OF BRAIN DISEASES AND CONDITIONS
(FR) COMPOSITIONS ET MÉTHODES POUR PRÉVENIR ET TRAITER DES PATHOLOGIES ET DES MALADIES CÉRÉBRALES
Abstract: front page image
(EN)Disclosed herein are compounds, extracts, and active fractions of the plant Geum japonicum and methods for preventing or treating brain diseases or conditions, such as ischemic stroke, Alzheimer's disease, vascular dementia, mild cognitive impairment (MCI), chronic cerebral ischemia and Parkinson's disease. The compounds provided herein can be formulated into pharmaceutical compositions and medicaments that are useful in the disclosed methods. Also provided are the use of the compounds and extracts in preparing pharmaceutical formulations and medicaments.
(FR)La présente invention concerne des composés, des extraits, et des fragments actifs de la plante Geum japonicum, ainsi que des méthodes permettant de prévenir ou de traiter des pathologies ou des maladies cérébrales, telles que l'accident ischémique cérébral, la maladie d'Alzheimer, la démence vasculaire, un trouble cognitif léger, l'ischémie cérébrale chronique et la maladie de parkinson. Les composés décrits dans cette invention peuvent être préparés sous forme de compositions pharmaceutiques et de médicaments qui sont utiles dans les méthodes susmentionnées. La présente invention concerne également l'utilisation de composés et d'extraits pour préparer des formulations pharmaceutiques et des médicaments.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)