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1. (WO2010143010) IDENTIFICATION, OPTIMIZATION AND USE OF SHARED HLA-B*0702 EPITOPES FOR IMMUNOTHERAPY
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/143010    International Application No.:    PCT/IB2009/006332
Publication Date: 16.12.2010 International Filing Date: 09.06.2009
IPC:
C07K 14/47 (2006.01), G01N 33/68 (2006.01), C07K 7/06 (2006.01)
Applicants: VAXON BIOTECH [FR/FR]; 3 rue de l' Arrivée 75749 Paris Cedex 15 (FR) (For All Designated States Except US).
KOSMATOPOULOS, Kostantinos (Kostas) [GR/FR]; (FR) (For US Only).
MENEZ-JAMET, Jeanne [FR/FR]; (FR) (For US Only)
Inventors: KOSMATOPOULOS, Kostantinos (Kostas); (FR).
MENEZ-JAMET, Jeanne; (FR)
Agent: MARCADÉ, Véronique; Cabinet ORES 36, rue de Saint-Pétersbourg F-75008 Paris (FR)
Priority Data:
Title (EN) IDENTIFICATION, OPTIMIZATION AND USE OF SHARED HLA-B*0702 EPITOPES FOR IMMUNOTHERAPY
(FR) IDENTIFICATION, OPTIMISATION ET UTILISATION D'ÉPITOPES HLA-B*0702 PARTAGÉS POUR L'IMMUNOTHÉRAPIE
Abstract: front page image
(EN)The present invention provides novel methods and materials for efficiently treating patients having an HLA-B*0702 phenotype, based on peptides representing shared epitopes of tumour antigens. In particular, the invention relates to a method for identifying a HLA-B*0702-restricted peptide which can trigger a cytotoxic response against several antigens from one single multigenic family, and to several such epitopes.
(FR)La présente invention concerne de nouveaux procédés et matériaux pour traiter efficacement des patients présentant un phénotype HLA-B*0702, à base de peptides représentant des épitopes partagés d'antigènes de tumeurs. L'invention concerne notamment un procédé d'identification d'un peptide restreint par HLA-B*0702 qui peut déclencher une réponse cytotoxique contre plusieurs antigènes d'une famille multigénique individuelle, et plusieurs de ces épitopes.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)