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Machine translation
1. (WO2010142656) HETEROCYCLIC ANTIVIRAL COMPOUNDS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/142656    International Application No.:    PCT/EP2010/057958
Publication Date: 16.12.2010 International Filing Date: 08.06.2010
Chapter 2 Demand Filed:    06.04.2011    
IPC:
C07D 213/69 (2006.01), C07D 239/46 (2006.01), C07D 401/04 (2006.01), C07D 401/10 (2006.01), C07D 401/14 (2006.01), C07D 403/10 (2006.01), A61K 31/444 (2006.01), A61K 31/4439 (2006.01), A61P 31/12 (2006.01)
Applicants: F. HOFFMANN-LA ROCHE AG [CH/CH]; Grenzacherstrasse 124 CH-4070 Basel (CH) (For All Designated States Except US).
DE VICENTE FIDALGO, Javier [ES/US]; (US) (For US Only).
LI, Jim [US/US]; (US) (For US Only).
SCHOENFELD, Ryan Craig [US/US]; (US) (For US Only).
TALAMAS, Francisco Xavier [US/US]; (US) (For US Only).
TAYGERLY, Joshua Paul Gergely [US/US]; (US) (For US Only)
Inventors: DE VICENTE FIDALGO, Javier; (US).
LI, Jim; (US).
SCHOENFELD, Ryan Craig; (US).
TALAMAS, Francisco Xavier; (US).
TAYGERLY, Joshua Paul Gergely; (US)
Agent: KJELLSAA-BERGER, Hanny; Grenzacherstrasse 124 CH-4070 Basel (CH)
Priority Data:
61/185,460 09.06.2009 US
61/263,351 21.11.2009 US
Title (EN) HETEROCYCLIC ANTIVIRAL COMPOUNDS
(FR) COMPOSÉS ANTIVIRAUX HÉTÉROCYCLIQUES
Abstract: front page image
(EN)Compounds having the formula (I) wherein wherein R1, R2, R3, R4, X1, X2, X3 and X4 and as defined herein are Hepatitis C virus NS5b polymerase inhibitors. Also disclosed are compositions and methods for treating an HCV infection and inhibiting HCV replication.
(FR)La présente invention a pour objet des composés ayant la formule (I), R1, R2, R3, R4, X1, X2, X3 et X4 étant tels que définis ici, qui sont des inhibiteurs de la polymérase NS5b du virus de l'hépatite C. La présente invention concerne aussi des compositions et des procédés pour le traitement d'une infection au VHC et l'inhibition de la réplication du VHC.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)