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1. (WO2010142630) IL-17 FOR USE IN TREATING LOCAL INFECTIONS IN MAMMALS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/142630    International Application No.:    PCT/EP2010/057898
Publication Date: 16.12.2010 International Filing Date: 07.06.2010
IPC:
A61K 38/20 (2006.01), A61P 31/00 (2006.01)
Applicants: LINDÉN, Anders [SE/SE]; (SE).
SILVERPIL, Elin [SE/SE]; (SE).
GLADER, Pernilla [SE/SE]; (SE)
Inventors: LINDÉN, Anders; (SE).
SILVERPIL, Elin; (SE).
GLADER, Pernilla; (SE)
Priority Data:
12/455,929 09.06.2009 US
Title (EN) IL-17 FOR USE IN TREATING LOCAL INFECTIONS IN MAMMALS
(FR) TRAITEMENT D'INFECTIONS LOCALES CHEZ LES MAMMIFÈRES
Abstract: front page image
(EN)An effective method is provided for local treatment against localized microbial infection, including abscesses, in skin and soft tissue and elsewhere in mammalian organs of an immuno-competent, immuno-compromised or immuno-deficient subject. The method employs mammalian IL-17 receptor agonists, which exert several antimicrobial actions, including the stimulation of neutrophil turnover as well as macrophage phagocytosis locally in an infected mammalian organ.
(FR)L'invention porte sur un procédé efficace pour un traitement local contre une infection microbienne localisée, comprenant des abcès, dans la peau et le tissu mou et ailleurs dans des organes de mammifère d'un sujet immunocompétent, immunocompromis ou immunodéficient. Le procédé emploie des agonistes du récepteur IL-17 de mammifère, qui exercent plusieurs actions antimicrobiennes, comprenant la stimulation du renouvellement des neutrophiles ainsi qu'une phagocytose par les macrophages localement dans un organe de mammifère infecté.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)