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1. (WO2010142241) HIGH PENETRATION COMPOSITIONS OR PRODRUGS OF ANTIMICROBIALS AND ANTIMICROBIAL-RELATED COMPOUNDS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/142241    International Application No.:    PCT/CN2010/073743
Publication Date: 16.12.2010 International Filing Date: 10.06.2010
IPC:
C07D 205/12 (2006.01), C07D 277/60 (2006.01), C07D 211/26 (2006.01), C07D 211/16 (2006.01), A61K 31/397 (2006.01), A61K 31/43 (2006.01), A61K 31/545 (2006.01), A61P 31/00 (2006.01), A61P 31/04 (2006.01)
Applicants: YU, Chongxi [US/US]; (US).
TECHFIELDS BIOCHEM CO., LTD. [CN/CN]; 2399 JinQiu Road, #129, Shanghai 200444 (CN) (For All Designated States Except US).
XU, Lina [CN/CN]; (CN) (For US Only).
CHEN, Yuhua [CN/CN]; (CN) (For US Only).
YAN, Binbing [CN/CN]; (CN) (For US Only).
TU, Shiqian [CN/CN]; (CN) (For US Only)
Inventors: YU, Chongxi; (US).
XU, Lina; (CN).
CHEN, Yuhua; (CN).
YAN, Binbing; (CN).
TU, Shiqian; (CN)
Agent: WAN HUI DA INTELLECTUAL PROPERTY AGENCY; 2F, Yiyuan Office Building, Friendship Hotel, No. 1 Zhongguancun Street South Beijing 100873 (CN)
Priority Data:
12/482,373 10.06.2009 US
200910141944.X 10.06.2009 CN
Title (EN) HIGH PENETRATION COMPOSITIONS OR PRODRUGS OF ANTIMICROBIALS AND ANTIMICROBIAL-RELATED COMPOUNDS
(FR) COMPOSITIONS À PÉNÉTRATION ÉLEVÉE OU PROMÉDICAMENTS DE COMPOSÉS ANTIMICROBIENS ET COMPOSÉS APPARENTÉS À DES ANTIMICROBIENS
Abstract: front page image
(EN)High penetration comp1ositions (HPCs) or prodrugs (HPPs) of antimicrobials and antimicrobial-related compounds are provided. The HPCs/HPPs are capable of being converted to parent drugs or drug metabolites after crossing the biological barrier and thus can render treatments. Additionally, the HPCs/HPPs are capable of reaching areas that their parent drugs may not be able to access and rendering a sufficient concentration at the target areas and therefore render novel treatments.
(FR)La présente invention concerne des compositions à pénétration élevée (HPC) ou des promédicaments à pénétration élevée (HPP) de composés antimicrobiens et apparentés à des antimicrobiens. Les HPC/HPP sont en mesure d'être convertis en médicaments parents ou métabolites de médicament après avoir traversé la barrière biologique et peuvent donc produire des traitements. De plus, les HPC/HPP sont capables d'atteindre des zones auxquelles leurs médicaments parents ne peuvent pas accéder et d'atteindre une concentration suffisante aux zones cibles et par conséquent, produire de nouveaux traitements.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)