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1. (WO2010141471) NUCLEIC ACID DELIVERY COMPOSITIONS AND METHODS OF USE THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/141471    International Application No.:    PCT/US2010/036905
Publication Date: 09.12.2010 International Filing Date: 01.06.2010
IPC:
C07H 21/02 (2006.01), C12N 15/113 (2010.01), A61K 31/7105 (2006.01), A61K 48/00 (2006.01)
Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA [US/US]; 1111 Franklin Street, 5th Floor Oakland, CA 94607-5200 (US) (For All Designated States Except US).
DOWDY, Steven, F. [US/US]; (US) (For US Only).
MEADE, Bryan [US/US]; (US) (For US Only).
GOGOI, Khirud [IN/IN]; (IN) (For US Only)
Inventors: DOWDY, Steven, F.; (US).
MEADE, Bryan; (US).
GOGOI, Khirud; (IN)
Agent: BAKER, Joseph, R., Jr.; Gavrilovich, Dodd & Lindsey LLP 4660 La Jolla Village Drive, Suite 750 San Diego, CA 92122 (US)
Priority Data:
61/182,832 01.06.2009 US
Title (EN) NUCLEIC ACID DELIVERY COMPOSITIONS AND METHODS OF USE THEREOF
(FR) COMPOSITIONS POUR L'ADMINISTRATION D'ACIDES NUCLÉIQUES ET PROCÉDÉS POUR LES UTILISER
Abstract: front page image
(EN)This disclosure relates to nucleic acid constructs modified to have a reduced net anionic charge. The constructs comprise phosphotriester and/or phosphothioate protecting groups. The disclosure also provides methods of making and using such constructs.
(FR)Cette invention concerne des constructions d'acide nucléique modifiées afin de réduire leur charge anionique nette. Les constructions comprennent des groupes protecteurs de phosphotriester et/ou de phosphothioate. Cette invention concerne également des procédés de préparation et d'utilisation de ces constructions.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)