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1. (WO2010140163) NON-IMPLANTABLE MEDICAL DEVICE COATED WITH ENCAPSULATED NANOPARTICLES CONTAINING THERAPEUTIC AGENTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/140163    International Application No.:    PCT/IN2010/000349
Publication Date: 09.12.2010 International Filing Date: 21.05.2010
IPC:
A61M 25/04 (2006.01), A61M 25/10 (2006.01), A61M 29/02 (2006.01), A61K 47/14 (2006.01), A61L 29/16 (2006.01)
Applicants: CONCEPT MEDICAL INC. [US/US]; 23611, Chargin Boulevard Suite 250 Beachwood, OH 44122 (US) (For All Designated States Except US).
DOSHI, Manish [IN/IN]; (IN) (For US Only).
SHERDIWALA, Divyesh [IN/IN]; (IN) (For US Only).
SOJITRA, Prakash [IN/IN]; (IN) (For US Only).
VYAS, Ashwin [IN/IN]; (IN) (For US Only).
GANDHI, Pankaj [IN/IN]; (IN) (For US Only)
Inventors: DOSHI, Manish; (IN).
SHERDIWALA, Divyesh; (IN).
SOJITRA, Prakash; (IN).
VYAS, Ashwin; (IN).
GANDHI, Pankaj; (IN)
Agent: RAJENDRAN, Arun; Nishith Desai Associates G-01, Prestige Loka 7/1, Brunton Road Bangalore 560 025 (IN)
Priority Data:
1337/MUM/2009 02.06.2009 IN
Title (EN) NON-IMPLANTABLE MEDICAL DEVICE COATED WITH ENCAPSULATED NANOPARTICLES CONTAINING THERAPEUTIC AGENTS
(FR) RAJEUNISSEMENT DES ARTÈRES CORONAIRES PAR AMÉLIORATION DU DÉBIT SANGUIN À L'AIDE DE NANOBILLES (NANOPARTICULES ENCAPSULÉES) INSÉRÉES CONTENANT DES AGENTS THÉRAPEUTIQUES PAR DES DISPOSITIFS NON IMPLANTABLES POUR TISSUS ET ASSURANT AINSI UNE LIBÉRATION DANS LES TISSUS POUR EXAMINER LE CYCLE CELLULAIRE NÉCESSAIRE
Abstract: front page image
(EN)A drug-delivering medical device for delivering a drug to a target site in a body lumen is disclosed. The drug-delivering medical device includes a balloon catheter and an inflatable balloon positioned on the balloon catheter. The inflatable balloon has a hydrophilic surface. One or more portions of the hydrophilic surface are coated with two or more nano-carriers. A nano-carrier of the two or more nano-carriers includes a drug surrounded by an encapsulating medium. As the drug is surrounded by the encapsulating medium, the surface of the nano-carrier is devoid of the drug. When the inflatable balloon is inflated upon coming in proximity to a target site in the body lumen, about 30% to 80% of the two or more nano-carriers are released from the hydrophilic surface within 15-90 seconds.
(FR)L'invention concerne un dispositif médical d'administration de médicaments pour administrer un médicament sur un site cible dans une lumière corporelle. Le dispositif médical d'administration de médicaments de l'invention comprend un cathéter à ballonnet et un ballonnet gonflable positionné sur ledit cathéter à ballonnet. Le ballonnet gonflable comprend une surface hydrophile. Une ou plusieurs parties de la surface hydrophile sont revêtues par au moins deux nano-supports. Un nano-support faisant partie des deux nano-supports ou plus comprend un médicament enrobé par un milieu d'encapsulation. Étant donné que le médicament est enrobé par le milieu d'encapsulation, la surface du nano-support est exempte du médicament. Lorsque le ballonnet gonflable est gonflé après être placé à proximité d'un site cible dans la lumière corporelle, environ 30 % à 80 % des deux nano-supports ou plus sont libérés à partir de la surface hydrophile dans les 15-90 secondes.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)