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1. (WO2010138820) N,N-DIARYLUREA COMPOUNDS AND N,N'-DIARYLTHIOUREA COMPOUNDS AS INHIBITORS OF TRANSLATION INITIATION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/138820    International Application No.:    PCT/US2010/036584
Publication Date: 02.12.2010 International Filing Date: 28.05.2010
IPC:
A61K 31/20 (2006.01), A61K 31/17 (2006.01)
Applicants: PRESIDENT AND FELLOWS OF HARVARD COLLEGE [US/US]; 17 Quincy Street Cambridge, MA 02138 (US) (For All Designated States Except US).
AKTAS, Huseyin [US/US]; (US) (For US Only).
HALPERIN, Jose, A. [US/US]; (US) (For US Only).
CHOREV, Michael [US/US]; (US) (For US Only)
Inventors: AKTAS, Huseyin; (US).
HALPERIN, Jose, A.; (US).
CHOREV, Michael; (US)
Agent: IWANICKI, JOHN P., 34628; Banner & Witcoff, LTD. 28 State Street, Suite 1800 Boston, MA 02109 (US)
Priority Data:
61/181,920 28.05.2009 US
Title (EN) N,N-DIARYLUREA COMPOUNDS AND N,N'-DIARYLTHIOUREA COMPOUNDS AS INHIBITORS OF TRANSLATION INITIATION
(FR) COMPOSÉS DE N,N'-DIARYLURÉE ET DE N,N'-DIARYLTHIOURÉE UTILISÉS EN TANT QU'INHIBITEURS DE L'INITIATION DE LA TRADUCTION
Abstract: front page image
(EN)Compositions and methods for inhibiting translation initiation are provided. Compositions, methods and kits for treating (1) cellular proliferative disorders, (2) non-proliferative, degenerative disorders, (3) viral infections, and/or (4) disorders associated with viral infections, using N,N'-diarylureas and/or N,N'-diarylthiourea compounds are described.
(FR)La présente invention concerne des compositions et des procédés permettant d'inhiber l'initiation de la traduction. L'invention concerne également des compositions, des procédés et des nécessaires permettant de traiter (1) des affections prolifératives cellulaires, (2) des affections dégénératives non prolifératives, (3) des infections virales et/ou (4) des affections associées à des infections virales, au moyen de N,N'-diarylurées et/ou de composés de N,N'-diarylthiourée.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)