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Machine translation
1. (WO2010137021) METHOD OF GENERATING CONNECTIVE TISSUE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/137021    International Application No.:    PCT/IL2010/000421
Publication Date: 02.12.2010 International Filing Date: 27.05.2010
IPC:
A61K 38/18 (2006.01), A61K 48/00 (2006.01), A61L 27/24 (2006.01), A61L 27/38 (2006.01), A61P 19/00 (2006.01)
Applicants: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. [IL/IL]; Hi Tech Park The Edmond J. Safra Campus The Hebrew University of Jerusalem Givat Ram 91390 Jerusalem (IL) (For All Designated States Except US).
GAZIT, Dan [IL/IL]; (IL) (For US Only).
PELLED, Gadi [IL/IL]; (IL) (For US Only).
GAZIT, Zulma [IL/IL]; (IL) (For US Only).
KIMELMAN-BLEICH, Nadav [IL/IL]; (IL) (For US Only)
Inventors: GAZIT, Dan; (IL).
PELLED, Gadi; (IL).
GAZIT, Zulma; (IL).
KIMELMAN-BLEICH, Nadav; (IL)
Agent: G.E. EHRLICH (1995) LTD.; 11 Menachem Begin Street Ramat Gan 52521 (IL)
Priority Data:
61/181,371 27.05.2009 US
Title (EN) METHOD OF GENERATING CONNECTIVE TISSUE
(FR) PROCÉDÉ DE GÉNÉRATION DE TISSU CONJONCTIF
Abstract: front page image
(EN)A method of generating bone or connective tissue in a subject in need thereof, the method comprising: (a) implanting a scaffold in a damaged region of the subject, the scaffold comprising a tissue growth promoting agent; and (b) enhancing uptake of the tissue growth promoting agent into cells located on the scaffold, wherein the enhancing is effected by induced poration of the cells thereby generating bone or connective tissue in the subject. Kits for generating bone or connective tissue are also provided.
(FR)La présente invention concerne un procédé de génération de tissu osseux ou conjonctif chez un sujet en ayant besoin, ledit procédé comprenant les étapes consistant (a) à implanter un support dans une zone lésée de l'organisme d'un sujet, ledit support comprenant un facteur favorisant la croissance tissulaire; et (b) à renforcer l'absorption dudit agent favorisant la croissance tissulaire par les cellules situées sur le support, ledit renforcement étant obtenu par une poration induite des cellules, avec pour résultat la génération de tissu osseux ou conjonctif chez le sujet. L'invention concerne également des nécessaires de génération de tissu osseux ou conjonctif.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)