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Pub. No.:    WO/2010/136752    International Application No.:    PCT/GB2010/001028
Publication Date: 02.12.2010 International Filing Date: 26.05.2010
C12N 5/079 (2010.01)
Applicants: UNIVERSITY OF THE WEST OF SCOTLAND [GB/GB]; High Street Paisley Renfrewshire PA1 2BE (GB) (For All Designated States Except US).
HASSAN, Hassan, Tawhid [GB/GB]; (GB) (For US Only).
GOODACRE, John, Alan [GB/GB]; (GB) (For US Only).
ZHAI, Xiao, Qun [CN/GB]; (GB) (For US Only)
Inventors: HASSAN, Hassan, Tawhid; (GB).
GOODACRE, John, Alan; (GB).
ZHAI, Xiao, Qun; (GB)
Agent: HARRISON IP LIMITED; 1st Floor, Box Tree House Northminster Business Park Northfield Lane York YO26 6QU (GB)
Priority Data:
0908934.3 26.05.2009 GB
Abstract: front page image
(EN)We disclose the preparation of a serum free differentiation medium comprising cell free human astrocyte conditioned medium and including a cell culture and method for the differentiation of neural stem cells/neural progenitor cells into differentiated neurones and their use in the repair of diseased or damage neural tissue and in drug screening.
(FR)La présente invention concerne la préparation d'un milieu de différenciation sans sérum comprenant un milieu conditionné par des astrocytes humains acellulaires, ainsi qu'une culture cellulaire et un procédé pour la différenciation des cellules souches neurales/cellules progénitrices neurales en neurones différenciés et leur utilisation dans la réparation de tissu neural malade ou lésé et dans le criblage de médicaments.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)