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1. (WO2010136694) INJECTABLE HYDROGEL FOR THE LONG-TERM SUPPLEMENTATION OF GLYCEROL IN THE SKIN
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2010/136694 International Application No.: PCT/FR2010/050937
Publication Date: 02.12.2010 International Filing Date: 14.05.2010
IPC:
A61L 27/20 (2006.01) ,A61L 27/52 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27
Materials for prostheses or for coating prostheses
14
Macromolecular materials
20
Polysaccharides
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27
Materials for prostheses or for coating prostheses
50
Materials characterised by their function or physical properties
52
Hydrogels or hydrocolloids
Applicants:
ANTEIS S.A. [CH/CH]; Chemin des Aulx 18 CH-1228 Plan-les-Ouates, CH (AllExceptUS)
GAVARD MOLLIARD, Samuel [FR/FR]; FR (UsOnly)
VINCHON, Cyrille [FR/FR]; FR (UsOnly)
Inventors:
GAVARD MOLLIARD, Samuel; FR
VINCHON, Cyrille; FR
Agent:
LAGET, Jean-Loup; Brema-Loyer Le Centralis 63, avenue du Général Leclerc F-92340 Bourg-la-Reine, FR
Priority Data:
095345226.05.2009FR
Title (EN) INJECTABLE HYDROGEL FOR THE LONG-TERM SUPPLEMENTATION OF GLYCEROL IN THE SKIN
(FR) HYDROGEL INJECTABLE PERMETTANT UNE SUPPLEMENTATION EN GLYCEROL DANS LA PEAU SUR LE LONG TERME
Abstract:
(EN) The present invention relates to an injectable hydrogel, including, in weight, in a physiologically acceptable carrier fluid: 0.01 to 5 % of glycerol and 0.1 to 5 % of cross-linked hyaluronic acid, or one of the salts thereof; characterized in that the hyaluronic acid or one of the salts thereof is cross-linked by the formation of covalent bonds using bifunctional or polyfunctional molecules, said injectable hydrogel being sterilized in moist heat and having viscoelastic properties such that Tanδ at a frequency of 1 Hz is less than or equal to 1.10. The present invention also relates to a method for producing said hydrogel, to a kit containing said hydrogel, as well as to the use thereof in dermatology.
(FR) La présente invention concerne un hydrogel injectable comprenant, en poids, dans un fluide vecteur physiologiquement acceptable : 0,01 % à 5 % de glycérol et 0,1 % à 5 % d'acide hyaluronique réticulé ou l'un de ses sels, caractérisé en ce que l'acide hyaluronique ou l'un de ses sels est réticulé par formation de liaisons covalentes à l'aide de molécules bi- ou polyfonctionnelles, ledit hydrogel injectable étant stérilisé à la chaleur humide et possédant des propriétés viscoélastiques telles que Tanδ à la fréquence de 1 Hz est inférieur ou égal à 1,10. La présente invention concerne également un procédé de fabrication dudit hydrogel, un kit contenant ledit hydrogel, ainsi que son utilisation en dermatologie.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: French (FR)
Filing Language: French (FR)
Also published as:
EP2435101US20120108674JP2012527926ES2406158BRPI1014924AU2010252816
FR2945949