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Machine translation
1. (WO2010136598) A COLLECTION AND METHODS FOR ITS USE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/136598    International Application No.:    PCT/EP2010/057507
Publication Date: 02.12.2010 International Filing Date: 29.05.2010
IPC:
C12N 15/10 (2006.01), C07K 16/00 (2006.01), C40B 30/02 (2006.01), C40B 40/08 (2006.01), C40B 50/06 (2006.01)
Applicants: MorphoSys AG [DE/DE]; Lena-Christ-Strasse 48 82152 Martinsried/Planegg (DE) (For All Designated States Except US).
ENZELBERGER, Markus [DE/DE]; (DE) (For US Only).
PRASSLER, Josef [DE/DE]; (DE) (For US Only).
URLINGER, Stefanie [DE/DE]; (DE) (For US Only).
HERRMANN, Tanja [DE/DE]; (DE) (For US Only).
TILLER, Thomas [DE/DE]; (DE) (For US Only)
Inventors: ENZELBERGER, Markus; (DE).
PRASSLER, Josef; (DE).
URLINGER, Stefanie; (DE).
HERRMANN, Tanja; (DE).
TILLER, Thomas; (DE)
Agent: HUTTER, Bernd; MorphoSys AG Lena-Christ-Str. 48 82152 Planegg-Martinsried (DE)
Priority Data:
61/182,350 29.05.2009 US
09162724.0 15.06.2009 EP
61/299,401 29.01.2010 US
Title (EN) A COLLECTION AND METHODS FOR ITS USE
(FR) COLLECTION ET SES PROCÉDÉS D'UTILISATION
Abstract: front page image
(EN)The present disclosure enables methods of identifying the VH and VL class pairs in the human immune repertoire, determining the VH and VL class pairs that are most prevalent and those having favorable biophysical properties. More specifically, the collections of the present disclosure comprise the most prevalent and/or preferred VH and VL class pairings with highly diversified CDRs.
(FR)La présente invention concerne des procédés d'identification de paires de domaines VH et VL dans le répertoire immunitaire humain, des procédés de détermination des paires de domaines VH et VL qui sont les plus prévalentes, ainsi que de celles qui présentent les propriétés biophysiques les plus intéressantes. De façon plus précise, les collections de la présente invention comprennent les paires de domaines VH et VL les plus prévalentes et/ou préférées, caractérisées par des régions déterminant la complémentarité hautement diversifiées.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)