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1. (WO2010136559) 2, 4 -DIAMINOPYRIMIDINES FOR THE TREATMENT OF DISEASES CHARACTERISED BY EXCESSIVE OR ABNORMAL CELL PROLIFERATION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/136559    International Application No.:    PCT/EP2010/057408
Publication Date: 02.12.2010 International Filing Date: 28.05.2010
IPC:
C07D 239/48 (2006.01), C07D 401/12 (2006.01), C07D 405/12 (2006.01), A61P 35/00 (2006.01), A61K 31/505 (2006.01)
Applicants: BOEHRINGER INGELHEIM INTERNATIONAL GMBH [DE/DE]; Binger Strasse 173 55216 Ingelheim am Rhein (DE) (For All Designated States Except US).
SAPOUNTZIS, Ioannis [GR/DE]; (DE) (For US Only).
STADTMUELLER, Heinz [DE/DE]; (DE) (For US Only).
KUHN, Daniel [DE/DE]; (DE) (For US Only)
Inventors: SAPOUNTZIS, Ioannis; (DE).
STADTMUELLER, Heinz; (DE).
KUHN, Daniel; (DE)
Agent: HAMMANN, Heinz, et al.; Boehringer Ingelheim GmbH Patents Germany Binger Strasse 173 55216 Ingelheim am Rhein (DE)
Priority Data:
09161496.6 29.05.2009 EP
10161628.2 30.04.2010 EP
Title (EN) 2, 4 -DIAMINOPYRIMIDINES FOR THE TREATMENT OF DISEASES CHARACTERISED BY EXCESSIVE OR ABNORMAL CELL PROLIFERATION
(FR) 2, 4-DIAMINOPYRIMIDINES POUR LE TRAITEMENT DE MALADIES CARACTÉRISÉES PAR UNE PROLIFÉRATION CELLULAIRE EXCESSIVE OU ANORMALE
Abstract: front page image
(EN)The present invention encompasses compounds of general formula (1), wherein A, B, R1 to R5, Rx m, n and p are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, pharmaceutical preparations which contain such compounds and the use thereof [as] medicaments.
(FR)La présente invention porte sur des composés de formule générale (1), dans laquelle A, B, R1 à R5, Rx m, n et p sont tels que définis dans la revendication 1, qui sont appropriés pour le traitement de maladies caractérisées par une prolifération cellulaire excessive ou anormale. L'invention porte également sur des préparations pharmaceutiques qui contiennent de tels composés et sur leur utilisation en tant que médicaments.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)