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1. (WO2010135976) 1-(SUBSTITUTED BENZYL)-5-TRIFLUOROMETHYL-2-(1H) PYRIDONE COMPOUNDS AND THEIR SALTS, THEIR PREPARATION METHODS AND USE THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/135976    International Application No.:    PCT/CN2010/073131
Publication Date: 02.12.2010 International Filing Date: 24.05.2010
IPC:
C07D 213/64 (2006.01), A61K 31/4412 (2006.01), A61P 43/00 (2006.01)
Applicants: CENTRAL SOUTH UNIVERSITY [CN/CN]; 172 Tongzipo Road Changsha, Hunan 410013 (CN) (For All Designated States Except US).
HU, Gaoyun [CN/CN]; (CN) (For US Only).
TAO, Lijian [CN/CN]; (CN) (For US Only).
CHEN, Jun [CN/CN]; (CN) (For US Only)
Inventors: HU, Gaoyun; (CN).
TAO, Lijian; (CN).
CHEN, Jun; (CN)
Agent: CHANGSHA ZONEKEY PANTENT LAW FIRM; 59# Bayi Road Changsha, Hunan 410001 (CN)
Priority Data:
200910043502.1 25.05.2009 CN
Title (EN) 1-(SUBSTITUTED BENZYL)-5-TRIFLUOROMETHYL-2-(1H) PYRIDONE COMPOUNDS AND THEIR SALTS, THEIR PREPARATION METHODS AND USE THEREOF
(FR) COMPOSÉS DE 1-(BENZYL SUBSTITUÉ)-5-TRIFLUOROMÉTHYL-2-(1H)-PYRIDONE ET DE LEURS SELS, LEURS PROCÉDÉS DE PRÉPARATION ET LEUR UTILISATION
(ZH) 1-(取代苄基)-5-三氟甲基-2-(1H)吡啶酮化合物及其盐,其制备方法及其用途
Abstract: front page image
(EN)1-(Substituted benzyl)-5-trifluoromethyl-2-(1H) pyridone compounds and their pharmaceutical acceptable salts are disclosed. The preparation methods of the compounds and their salts and the use of the same for preparing the medicaments for treating fibrosis are also disclosed. New pyridone compounds and their salts are obtained from trifluoromethyl pyridone as starting material.
(FR)L'invention porte sur des composés de 1-(benzyl substitué)-5-trifluorométhyl-2-(1H)-pyridone et sur leurs sels pharmaceutiquement acceptables. L'invention porte également sur les procédés de préparation de composés et de leurs sels et sur leur utilisation pour la préparation des médicaments pour le traitement d'une fibrose. Les nouveaux composés de pyridone et leurs sels sont obtenus à partir de trifluorométhylpyridone comme matière de départ.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)