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1. WO2010129544 - METHODS AND COMPUTER PROGRAM PRODUCTS FOR QUANTITATIVE THREE-DIMENSIONAL IMAGE CORRECTION AND CLINICAL PARAMETER COMPUTATION IN OPTICAL COHERENCE TOMOGRAPHY

Publication Number WO/2010/129544
Publication Date 11.11.2010
International Application No. PCT/US2010/033540
International Filing Date 04.05.2010
IPC
G01B 11/02 2006.01
GPHYSICS
01MEASURING; TESTING
BMEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
11Measuring arrangements characterised by the use of optical means
02for measuring length, width, or thickness
CPC
A61B 3/102
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
3Apparatus for testing the eyes; Instruments for examining the eyes
10Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
102for optical coherence tomography [OCT]
G01B 11/2441
GPHYSICS
01MEASURING; TESTING
BMEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
11Measuring arrangements characterised by the use of optical means
24for measuring contours or curvatures
2441using interferometry
G01B 9/02083
GPHYSICS
01MEASURING; TESTING
BMEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
9Instruments as specified in the subgroups and characterised by the use of optical measuring means
02Interferometers ; for determining dimensional properties of, or relations between, measurement objects
02083characterised by particular signal processing and presentation
G01B 9/02091
GPHYSICS
01MEASURING; TESTING
BMEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
9Instruments as specified in the subgroups and characterised by the use of optical measuring means
02Interferometers ; for determining dimensional properties of, or relations between, measurement objects
02091Tomographic low coherence interferometers, e.g. optical coherence tomography
G06T 15/00
GPHYSICS
06COMPUTING; CALCULATING; COUNTING
TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
153D [Three Dimensional] image rendering
G06T 2207/10101
GPHYSICS
06COMPUTING; CALCULATING; COUNTING
TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
2207Indexing scheme for image analysis or image enhancement
10Image acquisition modality
10072Tomographic images
10101Optical tomography; Optical coherence tomography [OCT]
Applicants
  • DUKE UNIVERSITY [US]/[US] (AllExceptUS)
  • IZATT, Joseph, A. [US]/[US] (UsOnly)
  • KUO, Anthony, N. [US]/[US] (UsOnly)
  • ZHAO, Mingtao [CN]/[US] (UsOnly)
Inventors
  • IZATT, Joseph, A.
  • KUO, Anthony, N.
  • ZHAO, Mingtao
Agents
  • WILSON, Jeffrey, L.
Priority Data
61/175,17004.05.2009US
61/276,76016.09.2009US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHODS AND COMPUTER PROGRAM PRODUCTS FOR QUANTITATIVE THREE-DIMENSIONAL IMAGE CORRECTION AND CLINICAL PARAMETER COMPUTATION IN OPTICAL COHERENCE TOMOGRAPHY
(FR) PROCÉDÉS ET PRODUITS-PROGRAMMES INFORMATIQUES POUR CORRECTION QUANTITATIVE D'IMAGE TRIDIMENSIONNELLE ET CALCUL DE PARAMÈTRE CLINIQUE POUR LA TOMOGRAPHIE À COHÉRENCE OPTIQUE
Abstract
(EN)
Methods and computer program products for quantitative three- dimensional ("3D") image correction in optical coherence tomography. Using the methods and computer program products, index interface (refracting) surfaces from the raw optical coherence tomography ("OCT") dataset from an OCT system can be segmented. Normal vectors or partial derivatives of the curvature at a refracting surface can be calculated to obtain a refracted image voxel. A new position of each desired refracted image voxel can be iteratively computed. New refracted corrected voxel positions to an even sampling grid can be interpolated to provide corrected image data. In some embodiments, clinical outputs from the corrected image data can be computed.
(FR)
La présente invention concerne des procédés et des produits-programmes informatiques pour corriger quantitativement des images tridimensionnelles (3D) pour la tomographie à cohérence optique. En utilisant ces procédés et produits-programmes informatiques, les surfaces d'interface d'indice (surfaces de réfringence) issues des jeux de données bruts de tomographie à cohérence optique (OCT) provenant d'un système d'OCT peuvent être segmentées. Des vecteurs normaux ou des dérivées partielles de la courbure sur une surface de réfringence peuvent être calculés pour obtenir un voxel d'image réfractée. Une nouvelle position de chaque voxel d'image réfractée désirée peut être calculée itérativement. De nouvelles positions corrigées de voxel d'image réfractée sur une même grille d'échantillonnage peuvent être interpolées pour fournir des données d'image corrigées. Dans certains modes de réalisation, des sorties cliniques provenant des données d'image corrigées peuvent être calculées.
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