Some content of this application is unavailable at the moment.
If this situation persists, please contact us atFeedback&Contact
1. (WO2010125201) RECOMBINANT VIRUS-LIKE PARTICLES ENCODED BY MULTI-GENE VECTOR
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2010/125201 International Application No.: PCT/EP2010/055943
Publication Date: 04.11.2010 International Filing Date: 30.04.2010
IPC:
C12N 7/04 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
7
Viruses, e.g. bacteriophages; Compositions thereof; Preparation or purification thereof
04
Inactivation or attenuation; Producing viral sub-units
Applicants:
REDBIOTEC AG [CH/CH]; Wagistrasse 23 CH-8952 Schlieren, CH (AllExceptUS)
JOHN, Corinne [DE/CH]; CH (UsOnly)
SCHAUB, Christian [CH/CH]; CH (UsOnly)
WELLNITZ, Sabine [DE/CH]; CH (UsOnly)
Inventors:
JOHN, Corinne; CH
SCHAUB, Christian; CH
WELLNITZ, Sabine; CH
Agent:
BECKER, Konrad; Aeschenvorstadt 24 Postfach 318 CH-4010 Basel, CH
Priority Data:
09159287.301.05.2009EP
Title (EN) RECOMBINANT VIRUS-LIKE PARTICLES ENCODED BY MULTI-GENE VECTOR
(FR) PARTICULES RECOMBINANTES DE TYPES VIRUS CODÉES PAR UN VECTEUR DE GÈNES MULTIPLES
Abstract:
(EN) The invention describes novel virus-like particles for use as vaccines, diagnostic tools and R&D tools based on recombinant DNA and cell cultivation techniques for production. The recombinant virus-like particles of the invention are assembled by polypeptide chains that incorporate several, in particular two or more, different epitopes which are selected either (a) from different viral strains of the same virus and/or (b) from different serotypes of the same virus and/or (c) from different viral strains specific for different hosts. These epitopes are then displayed on the particle surface.
(FR) L'invention concerne de nouvelles particules de type virus destinées à être utilisées comme vaccins, outils de diagnostic et outils de R&D sur la base d'ADN recombinant et de techniques de culture des cellules pour la production. Les particules recombinantes de type virus selon l'invention sont assemblées par des chaînes polypeptides qui incorporent plusieurs, en particulier deux ou plus de deux, épitopes différents qui sont sélectionnés (a) parmi différentes souches virales du même virus et/ou (b) parmi différents sérotypes du même virus et/ou (c) parmi différentes souches virales spécifiques pour différents hôtes. Ces épitopes sont ensuite exposés sur la surface des particules.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
SG175781IL216005EP2424980US20120064115JP2012525133CN102414313
CA2760524KR1020120018783SG10201603033QJP2016104015US20160194662EP2952581
NZ595710AU2010243489AU2014203512IN8756/CHENP/2011