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1. (WO2010124239) GENETIC POLYMORPHISMS ASSOCIATED WITH CLINICAL OUTCOMES OF TOPOISOMERASE INHIBITOR THERAPY FOR CANCER

Pub. No.:    WO/2010/124239    International Application No.:    PCT/US2010/032279
Publication Date: Fri Oct 29 01:59:59 CEST 2010 International Filing Date: Sat Apr 24 01:59:59 CEST 2010
IPC: C12Q 1/68
Applicants: UNIVERSITY OF SOUTHERN CALIFORNIA
LENZ, Heinz-Josef
Inventors: LENZ, Heinz-Josef
Title: GENETIC POLYMORPHISMS ASSOCIATED WITH CLINICAL OUTCOMES OF TOPOISOMERASE INHIBITOR THERAPY FOR CANCER
Abstract:
The invention provides compositions and methods for determining the likelihood of response or survival of cancer patients treated with topoisomerase inhibitor therapy or anti-EGFR and topoisomerase inhibitor therapy combination therapy. After determining if a patient is likely to be successfully treated, the invention also provides methods for treating the patients.