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1. (WO2010124198) AGGLOMERATE FORMULATIONS USEFUL IN DRY POWDER INHALERS
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2010/124198 International Application No.: PCT/US2010/032220
Publication Date: 28.10.2010 International Filing Date: 23.04.2010
IPC:
A61K 9/16 (2006.01) ,A61K 9/72 (2006.01) ,A61K 31/58 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
14
Particulate form, e.g. powders
16
Agglomerates; Granulates; Microbeadlets
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
72
for smoking or inhaling
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
56
Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
58
containing heterocyclic rings, e.g. aldosterone, danazol, stanozolol, pancuronium, digitogenin
Applicants:
PANDEY, Preetanshu [IN/US]; US (UsOnly)
CHAMARTHY, Sai Prasanth [US/IN]; US (UsOnly)
DONOVAN, Brent, Ashley [US/US]; US (UsOnly)
SCHERING CORPORATION [US/US]; 2000 Galloping Hill Road Kenilworth, New Jersey 07033, US (AllExceptUS)
Inventors:
PANDEY, Preetanshu; US
CHAMARTHY, Sai Prasanth; US
DONOVAN, Brent, Ashley; US
Agent:
JACOBSEN, Barry, H.; Merck & Co., Inc. 126 East Lincoln Avenue Rahway, NJ 07065, US
Priority Data:
61/172,34324.04.2009US
Title (EN) AGGLOMERATE FORMULATIONS USEFUL IN DRY POWDER INHALERS
(FR) PRÉPARATIONS D'AGGLOMÉRAT UTILES DANS DES INHALATEURS À POUDRE SÈCHE
Abstract:
(EN) Several embodiments of the present invention provide for an agglomerate useful for an agglomerate based dry powder inhaler comprising at least one active pharmaceutical agent, at least one additional functional excipient and at least one excipient, such as a binder. Useful at least one additional functional excipients include but are not limited to magnesium stearate, colloidal silica, silicon dioxide, sucrose stearate, L-leucine and combinations thereof.
(FR) Plusieurs modes de réalisation de la présente invention concernent un agglomérat utile pour un inhalateur à poudre sèche à base d'agglomérat comprenant au moins un agent pharmaceutique actif, au moins un excipient fonctionnel supplémentaire et au moins un excipient, tel qu'un liant. Un ou plusieurs excipients fonctionnels supplémentaires comprennent entre autres le stéarate de magnésium, la silice colloïdale, l'oxyde de silicium, le stéarate de sucrose, la L-leucine et leurs combinaisons.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)