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Pub. No.: WO/2010/124188 International Application No.: PCT/US2010/032208
Publication Date: 28.10.2010 International Filing Date: 23.04.2010
C07K 16/28 (2006.01) ,C07K 16/30 (2006.01) ,A61K 39/395 (2006.01)
Applicants: RADER, Christoph[US/US]; US (UsOnly)
BASKAR, Sivasubramanian[US/US]; US (UsOnly)
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES[US/US]; Office of Technology Transfer National Institutes of Health 6011 Executive Boulevard, Suite 325 MSC 7660 Bethesda, Maryland 20892-7660, US (AllExceptUS)
Inventors: RADER, Christoph; US
BASKAR, Sivasubramanian; US
Agent: COCHRAN, Christine M.; LEYDIG, VOIT & MAYER, LTD. Two Prudential Plaze, Suite 4900 180 N. Stetson Avenue Chicago, Illinois 60601, US
Priority Data:
Abstract: front page image
(EN) The invention relates to antibodies having specificity for human ROR1, compositions thereof, and methods for using such antibodies, including in the diagnosis and treatment of disorders associated with aberrant ROR1 expression.
(FR) La présente invention concerne des anticorps ayant une spécificité pour le gène ROR1 humain, des compositions associées, et des procédés d'utilisation desdits anticorps, notamment dans le diagnostic et le traitement de troubles associés à l'expression aberrante de ROR1.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)