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1. (WO2010124163) GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR (GM-CSF) NEUTRALIZING ANTIBODIES
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2010/124163 International Application No.: PCT/US2010/032170
Publication Date: 28.10.2010 International Filing Date: 23.04.2010
IPC:
C07K 16/24 (2006.01) ,A61K 39/395 (2006.01) ,A61P 35/00 (2006.01) ,A61P 29/02 (2006.01)
Applicants: CHAN-HUI, Po-Ying[US/US]; US (UsOnly)
FREY, Steven[US/US]; US (UsOnly)
GRANDEA, Andres, G.[US/US]; US (UsOnly)
COX, Thomas C.[US/US]; US (UsOnly)
THERACLONE SCIENCES, INC.[US/US]; Seattle Life Sciences Building 1124 Columbia Street, Suite 300 Seattle, WA 98104, US (AllExceptUS)
Inventors: CHAN-HUI, Po-Ying; US
FREY, Steven; US
GRANDEA, Andres, G.; US
COX, Thomas C.; US
Agent: ELRIFI, Ivor R; Mintz Levin Cohn Ferris Glovsky and Popeo, P.C. One Financial Center Boston, MA 02111, US
Priority Data:
61/172,12023.04.2009US
61/234,94618.08.2009US
Title (EN) GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR (GM-CSF) NEUTRALIZING ANTIBODIES
(FR) ANTICORPS NEUTRALISANT LE FACTEUR DE CROISSANCE DES GRANULOCYTES ET DES MACROPHAGES (GM-CSF)
Abstract: front page image
(EN) The invention provides a GM-CSF neutralizing human monoclonal antibody, 1783J22, as well as methods of making and use thereof. The monoclonal antibody is further characterized by its ability to bind epitopes from GM-CSF proteins of multiple species.
(FR) L'invention concerne un anticorps monoclonal humain 1783J22 neutralisant le GM-CSF, ainsi que des procédés pour le préparer et l'utiliser. L'anticorps monoclonal est en outre caractérisé par sa capacité à se lier aux épitopes de protéines GM-CSF de multiples espèces.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)