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1. (WO2010124143) REPROGRAMMING OF SOMATIC CELLS WITH PURIFIED PROTEINS

Pub. No.:    WO/2010/124143    International Application No.:    PCT/US2010/032131
Publication Date: Fri Oct 29 01:59:59 CEST 2010 International Filing Date: Fri Apr 23 01:59:59 CEST 2010
IPC: C12N 5/00
C12N 5/071
Applicants: NEVADA CANCER INSTITUTE
XU, C. Wilson
Inventors: XU, C. Wilson
Title: REPROGRAMMING OF SOMATIC CELLS WITH PURIFIED PROTEINS
Abstract:
Purified somatic cell reprogramming factors are described herein. The factors are particularly useful alone or in combination with at least one effector of cellular metabolism, in order to generate at least one reprogramming somatic cell. Methods for using at least one somatic cell reprogramming factor and at least one somatic cell reprogramming enhancing factor are provided. Additionally, the cells generated from the methods are also described. The methods and cells may find use in personalized medicine applications.