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1. (WO2010124102) AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/124102    International Application No.:    PCT/US2010/032068
Publication Date: 28.10.2010 International Filing Date: 22.04.2010
IPC:
C07D 401/12 (2006.01), C07D 403/12 (2006.01), C07D 403/14 (2006.01), C07D 409/12 (2006.01), C07D 417/12 (2006.01), C07D 417/14 (2006.01), C07D 495/04 (2006.01), A61K 31/496 (2006.01), A61P 25/00 (2006.01), A61P 29/00 (2006.01)
Applicants: JANSSEN PHARMACEUTICA NV [BE/BE]; Turnhoutseweg 30 B-2340 Beerse (BE) (For All Designated States Except US).
BIAN, Haiyan [US/US]; (US) (For US Only).
CHEVALIER, Kristen, M. [US/US]; (US) (For US Only).
CONNOLLY, Peter, J. [US/US]; (US) (For US Only).
FLORES, Christopher, M. [US/US]; (US) (For US Only).
LIN, Shu-Chen [CN/US]; (US) (For US Only).
LIU, Li [US/US]; (US) (For US Only).
MABUS, John [US/US]; (US) (For US Only).
MACIELAG, Mark, J. [US/US]; (US) (For US Only).
MCDONNELL, Mark, E. [US/US]; (US) (For US Only).
PITIS, Philip, M. [US/US]; (US) (For US Only).
ZHANG, Sui-Po [US/US]; (US) (For US Only).
ZHANG, Yue-Mei [US/US]; (US) (For US Only).
ZHU, Bin [US/US]; (US) (For US Only).
CLEMENTE, Jose [US/US]; (US) (For US Only)
Inventors: BIAN, Haiyan; (US).
CHEVALIER, Kristen, M.; (US).
CONNOLLY, Peter, J.; (US).
FLORES, Christopher, M.; (US).
LIN, Shu-Chen; (US).
LIU, Li; (US).
MABUS, John; (US).
MACIELAG, Mark, J.; (US).
MCDONNELL, Mark, E.; (US).
PITIS, Philip, M.; (US).
ZHANG, Sui-Po; (US).
ZHANG, Yue-Mei; (US).
ZHU, Bin; (US).
CLEMENTE, Jose; (US)
Agent: JOHNSON, Philip, S.; Johnson & Johnson One Johnson & Johnson Plaza New Brunswick, NJ 08933 (US)
Priority Data:
61/171,658 22.04.2009 US
61/171,649 22.04.2009 US
Title (EN) AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS
(FR) AZÉTIDINYL DIAMIDES EN TANT QU'INHIBITEURS DE LA MONOACYLGLYCÉROL LIPASE
Abstract: front page image
(EN)Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula (I) - see formula I - wherein Y, Z, R1, and s are defined herein.
(FR)L'invention porte sur des composés, des compositions et des procédés pour traiter différente maladies, syndromes, états pathologiques et troubles, y compris la douleur. Ces composés sont représentés par la Formule (I) – voir formule I -, dans laquelle Y, Z, R1 et s sont définis présentement.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)