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1. (WO2010122817) RESIN PRODUCT FOR MEDICAL USE AND RESPIRATION-ASSISTING TUBE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/122817    International Application No.:    PCT/JP2010/002977
Publication Date: 28.10.2010 International Filing Date: 26.04.2010
IPC:
A61L 31/00 (2006.01), A61L 29/00 (2006.01)
Applicants: NEXT21 K.K. [JP/JP]; Hongo Ishiwata Building 8F, 3-38-1, Hongo, Bunkyo-ku, Tokyo 1130033 (JP) (For All Designated States Except US).
THE UNIVERSITY OF TOKYO [JP/JP]; 3-1, Hongo 7-chome, Bunkyo-ku, Tokyo 1138654 (JP) (For All Designated States Except US).
NOF CORPORATION [JP/JP]; Yebisu Garden Place Tower, 20-3 Ebisu 4-chome, Shibuya-ku, Tokyo 1506019 (JP) (For All Designated States Except US).
TEI, Yuichi [JP/JP]; (JP) (For US Only).
SASAKI, Nobuo [JP/JP]; (JP) (For US Only).
SUZUKI, Shigeki [JP/JP]; (JP) (For US Only)
Inventors: TEI, Yuichi; (JP).
SASAKI, Nobuo; (JP).
SUZUKI, Shigeki; (JP)
Agent: HIROSE, Takayuki; c/o Hirose International Patent Firm, The Royal Building 3F, 3-8-7, Irihune, Chuo-ku, Tokyo 1040042 (JP)
Priority Data:
2009-105782 24.04.2009 JP
2009-256883 10.11.2009 JP
Title (EN) RESIN PRODUCT FOR MEDICAL USE AND RESPIRATION-ASSISTING TUBE
(FR) PRODUIT À BASE DE RÉSINE À USAGE MÉDICAL ET TUBE D'ASSISTANCE RESPIRATOIRE
(JA) 医療用樹脂製製品及び呼吸補助チューブ
Abstract: front page image
(EN)Disclosed is a respiration-assisting tube whereby tissue damages in vivo can be prevented and, as a result, inflammatory reactions and infections can be avoided. The respiration-assisting tube is developed based on the finding that adhesion of cells to a respiration-assisting tube can be inhibited by coating the respiration-assisting tube with a polymer containing 2-methacryloyloxyethyl phosphorylcholine (MPC). Also, the respiration-assisting tube is developed based on the finding that, by coating a respiration-assisting tube with a polymer containing MPC, mucosa peeling and tissue damages, which occur after using the respiration-assisting tube, can be prevented and, as a result, inflammatory reactions can be avoided.
(FR)L'invention concerne un tube d'assistance respiratoire permettant d'éviter les dommages tissulaires in vivo, et en conséquence les réactions inflammatoires et les infections. On a développé un tube d'assistance respiratoire sur la base de la découverte qu'il est possible d'inhiber l'adhérence des cellules sur le tube d'assistance respiratoire par revêtement de ce dernier au moyen d'un polymère contenant 2-methacryloyloxyethyl phosphorylcholine (MPC). On a également développé le tube d'assistance respiratoire sur la base de la découverte que le revêtement de ce dernier au moyen d'un polymère contenant MPC permet d'éviter le décollement des muqueuses et les dommages tissulaires qui se produisent suite à l'utilisation d'un tube d'assistance respiratoire, et en conséquence, les réactions inflammatoires.
(JA) 【課題】 本発明は,生体内の組織の損傷を防ぐことができ,その結果,炎症反応および,感染を回避することができる呼吸補助チューブを提供することを目的とする。 【課題手段】 本発明は,2-メタクリロイルオキシエチルホスホリルコリンを含むポリマーで呼吸補助チューブをコーティングすることで,呼吸補助チューブへの細胞接着を抑制することができるという知見に基づくものである。さらに,本発明はMPCを含むポリマーで呼吸補助チューブをコーティングすることで,呼吸補助チューブ使用後の粘膜剥離,組織損傷を防ぐことができ,その結果,炎症反応を回避することができるという知見に基づくものである。 
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)